159047

• Gene Symbol: Hspd1
• Gene Name: heat shock protein 1 (chaperonin)
• Gene Aliases: 60kDa, Hsp60
• Chromosome Location: Chr.1: 55077834 - 55088112 on Build GRCm38
• UniGene ID: Mm.1777
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Hspd1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_010477.4	NP_034607.3	2	276
GenBank mRNA	AK088844.1	-	2	190
	AK143882.1	-	2	181
	AK146831.1	-	2	228
	AK218891.1	-	2	169
	AK219639.1	-	1	20
	BC016400.1	-	2	162	3585270
	BC106112.1	-	2	177
	BY014148.1	-	2	285
	X53584.1	-	1	66
	X55023.1	-	2	138

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_199440, NM_002156, BC002676, AU098504, AK298844, and others.
This siRNA also targets the following transcripts in Rat: NM_022229, XM_006244932, X53585, BC086507, X54793.

Gene Ontology Categories:

Process(es)

detection of misfolded protein
B cell cytokine production
MyD88-dependent toll-like receptor signaling pathway
positive regulation of T cell mediated immune response to tumor cell
protein folding
activation of cysteine-type endopeptidase activity involved in apoptotic process
response to unfolded protein
positive regulation of interferon-alpha production
positive regulation of interferon-gamma production
positive regulation of interleukin-10 production
positive regulation of interleukin-12 production
positive regulation of interleukin-6 production
protein refolding
B cell proliferation
T cell activation
B cell activation
positive regulation of macrophage activation
positive regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of neuron apoptotic process
isotype switching to IgG isotypes
positive regulation of inflammatory response
protein stabilization
positive regulation of T cell activation
chaperone mediated protein folding requiring cofactor

Function(s)

nucleotide binding
lipopolysaccharide binding
protease binding
p53 binding
double-stranded RNA binding
ATP binding
ubiquitin protein ligase binding
protein complex binding
insulin binding
poly(A) RNA binding
protein heterodimerization activity
chaperone binding
misfolded protein binding