159759

• Gene Symbol: Atm
• Gene Name: ataxia telangiectasia mutated
• Gene Aliases: AI256621, C030026E19Rik
• Chromosome Location: Chr.9: 53437122 - 53536816 on Build GRCm38
• UniGene ID: Mm.5088
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Atm
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_007499.2	NP_031525.2	6	792
GenBank mRNA	AK139863.1	-	6	796
	BC138525.1	-	5	694	8861545
	U43678.1	-	5	694

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001106821, XM_006243068, XM_008766222.

Gene Ontology Categories:

Process(es)

DNA damage checkpoint
telomere maintenance
double-strand break repair via homologous recombination
response to hypoxia
somitogenesis
pre-B cell allelic exclusion
DNA repair
protein phosphorylation
cellular response to DNA damage stimulus
DNA damage induced protein phosphorylation
cell cycle
cell cycle arrest
mitotic spindle assembly checkpoint
female gamete generation
brain development
heart development
determination of adult lifespan
intrinsic apoptotic signaling pathway in response to DNA damage
response to ionizing radiation
phosphorylation
histone phosphorylation
peptidyl-serine phosphorylation
negative regulation of B cell proliferation
V(D)J recombination
histone-serine phosphorylation
phosphatidylinositol-3-phosphate biosynthetic process
lipoprotein catabolic process
positive regulation of apoptotic process
positive regulation of DNA damage response, signal transduction by p53 class mediator
positive regulation of neuron apoptotic process
protein autophosphorylation
phosphatidylinositol phosphorylation
oocyte development
neuron apoptotic process
regulation of cell cycle
histone mRNA catabolic process
cellular response to gamma radiation
signal transduction involved in mitotic G2 DNA damage checkpoint
replicative senescence

Function(s)

nucleotide binding
DNA binding
protein kinase activity
protein serine/threonine kinase activity
DNA-dependent protein kinase activity
protein binding
ATP binding
kinase activity
1-phosphatidylinositol-3-kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
phosphotransferase activity, alcohol group as acceptor
protein complex binding
histone serine kinase activity
protein dimerization activity
protein N-terminus binding