160548

• Gene Symbol: Dlg4
• Gene Name: discs, large homolog 4 (Drosophila)
• Gene Aliases: Dlgh4, PSD-95, PSD95, SAP90, SAP90A
• Chromosome Location: Chr.11: 70018455 - 70045532 on Build GRCm38
• UniGene ID: Mm.27256
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Dlg4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001109752.1	NP_001103222.1	10	1474
	NM_007864.3	NP_031890.1	10	1483
GenBank mRNA	BC014807.1	-	10	1219	4501403
	BQ959940.1	-	4	626
	D50621.1	-	10	1225

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001128827, NM_001365, AK297346, AK299801, U83192, and others.
This siRNA also targets the following transcripts in Rat: NM_019621, XM_006246686, XM_006246689, XM_006246681, XM_006246687, and others.

Gene Ontology Categories:

Process(es)

negative regulation of receptor internalization
protein complex assembly
signal transduction
positive regulation of cytosolic calcium ion concentration
chemical synaptic transmission
nervous system development
locomotory behavior
synaptic vesicle maturation
social behavior
protein localization to synapse
locomotory exploration behavior
response to cocaine
establishment of protein localization
nucleotide phosphorylation
regulation of neuronal synaptic plasticity
regulation of long-term neuronal synaptic plasticity
positive regulation of synaptic transmission
neuromuscular process controlling balance
dendritic spine morphogenesis
vocalization behavior
AMPA glutamate receptor clustering
receptor localization to synapse
regulation of N-methyl-D-aspartate selective glutamate receptor activity
positive regulation of excitatory postsynaptic potential
regulation of grooming behavior

Function(s)

guanylate kinase activity
receptor binding
structural molecule activity
protein binding
protein C-terminus binding
kinase binding
protein kinase binding
protein phosphatase binding
PDZ domain binding
beta-1 adrenergic receptor binding
D1 dopamine receptor binding
P2Y1 nucleotide receptor binding
protein complex binding
acetylcholine receptor binding
glutamate receptor binding
ionotropic glutamate receptor binding
neurexin family protein binding
neuroligin family protein binding
scaffold protein binding