163454

• Gene Symbol: Rapgef1
• Gene Name: Rap guanine nucleotide exchange factor (GEF) 1
• Gene Aliases: 4932418O06Rik, C3G, Grf2
• Chromosome Location: Chr.2: 29619720 - 29740364 on Build GRCm38
• UniGene ID: Mm.298274
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Rapgef1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001039086.1	NP_001034175.1	2	390
	NM_001039087.1	NP_001034176.1	2	390
	NM_054050.2	NP_473391.1	2	390
GenBank mRNA	AF348669.1	-	2	346
	AK147468.1	-	2	391
	AK147470.1	-	2	391
	AK147506.1	-	2	359
	AK147696.1	-	2	370
	BC129881.1	-	2	200	40110588

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_005312, NM_198679, BC041710, D21239, BG429001, and others.
This siRNA also targets the following transcripts in Rat: XM_008761683, XM_008761684, XM_008761687, XM_006233902, XM_008761685, and others.

Gene Ontology Categories:

Process(es)

blood vessel development
signal transduction
positive regulation of signal transduction
positive regulation of neuron projection development
single organismal cell-cell adhesion
Rap protein signal transduction
nerve growth factor signaling pathway
positive regulation of GTPase activity
negative regulation of Ras protein signal transduction
platelet-derived growth factor receptor signaling pathway
negative regulation of protein kinase B signaling
establishment of endothelial barrier
negative regulation of ERK1 and ERK2 cascade
cellular response to cAMP
negative regulation of canonical Wnt signaling pathway
regulation of cell junction assembly
cellular response to nerve growth factor stimulus
negative regulation of neural precursor cell proliferation

Function(s)

signal transducer activity
SH3/SH2 adaptor activity
guanyl-nucleotide exchange factor activity
protein binding
Rap guanyl-nucleotide exchange factor activity