172567

• Gene Symbol: Adrbk1
• Gene Name: adrenergic receptor kinase, beta 1
• Gene Aliases: Adrbk-1, Bark-1, GRK2, beta ARK, betaARK1
• Chromosome Location: Chr.19: 4285999 - 4306222 on Build GRCm38
• UniGene ID: Mm.254144
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Adrbk1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001290818.1	NP_001277747.1	6	669
	NM_130863.2	NP_570933.1	7	741
GenBank mRNA	AF333028.1	-	6	461
	AK155691.1	-	6	670
	BC003196.1	-	6	457
	BC033272.1	-	6	526
	BC053922.1	-	7	474	6309555

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_012776, M87854.

Gene Ontology Categories:

Process(es)

regulation of the force of heart contraction
desensitization of G-protein coupled receptor protein signaling pathway
negative regulation of the force of heart contraction by chemical signal
protein phosphorylation
response to oxidative stress
signal transduction
G-protein coupled receptor signaling pathway
tachykinin receptor signaling pathway
heart development
response to organic cyclic compound
phosphorylation
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
viral genome replication
receptor internalization
positive regulation of catecholamine secretion
termination of G-protein coupled receptor signaling pathway
follicle-stimulating hormone signaling pathway
negative regulation of G-protein coupled receptor protein signaling pathway
negative regulation of striated muscle contraction
viral entry into host cell
cardiac muscle contraction

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
G-protein coupled receptor kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
Edg-2 lysophosphatidic acid receptor binding
beta-adrenergic receptor kinase activity