1741

• Gene Symbol: DRD3
• Gene Name: dopamine receptor D3
• Gene Aliases: D3DR, ETM1, FET1
• Chromosome Location: Chr.3: 114127623 - 114199407 on Build GRCh38
• UniGene ID: Hs.121478
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DRD3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000796.5	NP_000787.2	3	716
	NM_001282563.2	NP_001269492.1	4	575
	NM_001290809.1	NP_001277738.1	4	708
	NM_033663.5	NP_387512.3	3	716
	XM_017005829.1	XP_016861318.1	4	536
GenBank mRNA	AK292309.1	-	4	575
	BC095510.1	-	2	286	7001986
	BC128122.1	-	4	630	40112299
	BC128123.1	-	3	362	40112300
	KJ534829.1	-	2	285
	L20469.1	-	2	285
	U32499.1	-	2	285

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_017140, XM_006248313, X53944.
This siRNA also targets the following transcripts in Mouse: NM_007877, BC119286, BC137819, X67274.

• Set Membership: G-protein coupled receptor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
synaptic transmission, dopaminergic
response to amphetamine
regulation of blood volume by renin-angiotensin
G-protein coupled receptor internalization
cellular calcium ion homeostasis
G-protein coupled receptor signaling pathway
adenylate cyclase-activating dopamine receptor signaling pathway
negative regulation of adenylate cyclase activity
adenylate cyclase-inhibiting dopamine receptor signaling pathway
learning or memory
learning
locomotory behavior
positive regulation of cell proliferation
visual learning
regulation of dopamine secretion
regulation of lipid metabolic process
regulation of cAMP metabolic process
negative regulation of sodium:proton antiporter activity
positive regulation of cytokinesis
circadian regulation of gene expression
response to histamine
social behavior
gastric emptying
positive regulation of renal sodium excretion
regulation of multicellular organism growth
response to cocaine
dopamine metabolic process
response to drug
response to morphine
regulation of circadian sleep/wake cycle, sleep
response to ethanol
negative regulation of blood pressure
positive regulation of mitotic nuclear division
positive regulation of transcription from RNA polymerase II promoter
acid secretion
behavioral response to cocaine
negative regulation of oligodendrocyte differentiation
arachidonic acid secretion
negative regulation of protein secretion
musculoskeletal movement, spinal reflex action
regulation of dopamine uptake involved in synaptic transmission
negative regulation of protein kinase B signaling
prepulse inhibition
negative regulation of dopamine receptor signaling pathway
positive regulation of dopamine receptor signaling pathway
regulation of locomotion involved in locomotory behavior

Function(s)

dopamine neurotransmitter receptor activity, coupled via Gs
dopamine neurotransmitter receptor activity, coupled via Gi/Go
protein binding
drug binding
protein domain specific binding
D1 dopamine receptor binding
dopamine binding