17556

• Gene Symbol: DLC1
• Gene Name: DLC1 Rho GTPase activating protein
• Gene Aliases: ARHGAP7, HP, STARD12, p122-RhoGAP
• Chromosome Location: Chr.8: 13083361 - 13604606 on Build GRCh38
• UniGene ID: Hs.134296
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DLC1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001164271.1	NP_001157743.1	9, 10	2499
	NM_001316668.1	NP_001303597.1	9, 10	2687
	NM_006094.4	NP_006085.2	9, 10	2757
	NM_182643.2	NP_872584.2	13, 14	4192
	XM_005273374.1	XP_005273431.1	13, 14	4073
	XM_017012951.1	XP_016868440.1	13, 14	3943
	XM_017012952.1	XP_016868441.1	9, 10	2490
GenBank mRNA	AB051510.1	-	13, 14	4078
	AF026219.1	-	9, 10	2710
	AF035119.1	-	9, 10	2761
	AK025544.1	-	9, 10	2686
	AK025733.1	-	4, 5	933
	AK289734.1	-	9, 10	2680
	AK291682.1	-	13, 14	4033
	AK299049.1	-	9, 10	2499
	BC054511.1	-	13, 14	3947	5240161

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: AK040846.

Gene Ontology Categories:

Process(es)

neural tube closure
heart morphogenesis
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
signal transduction
negative regulation of cell proliferation
regulation of cell shape
hindbrain morphogenesis
actin cytoskeleton organization
negative regulation of cell migration
forebrain development
regulation of actin cytoskeleton organization
negative regulation of Rho protein signal transduction
positive regulation of protein dephosphorylation
positive regulation of GTPase activity
focal adhesion assembly
regulation of small GTPase mediated signal transduction
negative regulation of stress fiber assembly
negative regulation of focal adhesion assembly
positive regulation of execution phase of apoptosis

Function(s)

GTPase activator activity
protein binding
lipid binding
SH2 domain binding