179674

• Gene Symbol: Pkp2
• Gene Name: plakophilin 2
• Gene Aliases: 1200008D14Rik, 1200012P04Rik, AA516617, Pkp2l
• Chromosome Location: Chr.16: 16213345 - 16272712 on Build GRCm38
• UniGene ID: Mm.2252
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pkp2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_026163.2	NP_080439.1	13	2525
GenBank mRNA	AK004650.1	-	13	2526
	AK049481.1	-	13	2526
	BC018487.1	-	7	1082
	BC037133.1	-	8	1131
	BC138252.1	-	13	2526	8861271
	BC138253.1	-	13	2525	8861272

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001100499, BC092602.

Gene Ontology Categories:

Process(es)

desmosome assembly
heart development
negative regulation of cell proliferation
gap junction assembly
single organismal cell-cell adhesion
negative regulation of cell migration
adherens junction maintenance
intermediate filament bundle assembly
maintenance of organ identity
ventricular cardiac muscle tissue morphogenesis
lipid homeostasis
cardiac muscle cell action potential
cardiac muscle cell action potential involved in contraction
ventricular cardiac muscle cell action potential
cell-cell signaling involved in cardiac conduction
bundle of His cell-Purkinje myocyte adhesion involved in cell communication
regulation of heart rate by cardiac conduction
establishment of protein localization to plasma membrane
regulation of ventricular cardiac muscle cell action potential
regulation of bicellular tight junction assembly

Function(s)

protein kinase C binding
protein binding
intermediate filament binding
protein complex scaffold
alpha-catenin binding