185299

• Gene Symbol: Plek
• Gene Name: pleckstrin
• Gene Aliases: 2010300B13Rik
• Chromosome Location: Chr.11: 16971206 - 17008718 on Build GRCm38
• UniGene ID: Mm.479819
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Plek
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_019549.2	NP_062422.1	2, 3	321
GenBank mRNA	AF073294.1	-	2, 3	305
	AF181829.1	-	2, 3	265
	AF303745.1	-	2, 3	253
	AK033872.1	-	2, 3	259
	AK038804.1	-		359
	AK050340.1	-	2, 3	263
	AK075810.1	-	2, 3	265
	AK138831.1	-	2, 3	259
	AK151460.1	-	2, 3	233
	AK152501.1	-	2, 3	233
	AK153109.1	-	2, 3	233
	AK156235.1	-	2, 3	322
	BC066185.1	-	2, 3	247	30433827

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001025750, XM_006251520, FQ232611, BC098846, FQ225547.

Gene Ontology Categories:

Process(es)

vesicle docking involved in exocytosis
integrin-mediated signaling pathway
positive regulation of platelet activation
negative regulation of inositol phosphate biosynthetic process
positive regulation of inositol-polyphosphate 5-phosphatase activity
cell projection organization
positive regulation of actin filament depolymerization
phospholipase C-inhibiting G-protein coupled receptor signaling pathway
cortical actin cytoskeleton organization
ruffle organization
actin cytoskeleton reorganization
positive regulation of actin filament bundle assembly
positive regulation of integrin activation
intracellular signal transduction
negative regulation of G-protein coupled receptor protein signaling pathway
phosphatidylinositol metabolic process
regulation of cell diameter
thrombin receptor signaling pathway
platelet aggregation
protein kinase C signaling
protein secretion by platelet

Function(s)

protein kinase C binding
protein homodimerization activity
phosphatidylinositol-3,4-bisphosphate binding