187828

• Gene Symbol: Map2k5
• Gene Name: mitogen-activated protein kinase kinase 5
• Gene Aliases: AI324775, AI428457, MEK5, Mapkk5, Prkmk5
• Chromosome Location: Chr.9: 63163768 - 63378438 on Build GRCm38
• UniGene ID: Mm.325746
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Map2k5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_011840.2	NP_035970.1	15	1547
GenBank mRNA	AB019374.1	-	15	1548
	AK013856.1	-	7	390
	AK159261.1	-	15	1597
	BC028260.1	-	15	1427	5067818

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001206804, NM_145160, NM_002757, U71087, AK057521, and others.
This siRNA also targets the following transcripts in Rat: NM_017246, NM_001033987, XM_008766221, XM_006243229, BC078860, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
MAPK cascade
activation of MAPK activity
protein phosphorylation
heart development
phosphorylation
positive regulation of cell growth
negative regulation of NF-kappaB transcription factor activity
negative regulation of heterotypic cell-cell adhesion
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of interleukin-8 biosynthetic process
positive regulation of transcription from RNA polymerase II promoter
positive regulation of epithelial cell proliferation
positive regulation of protein metabolic process
negative regulation of response to cytokine stimulus
ERK5 cascade
cellular response to growth factor stimulus
negative regulation of cell migration involved in sprouting angiogenesis
negative regulation of chemokine (C-X-C motif) ligand 2 production
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase activity
protein tyrosine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
metal ion binding