188082

• Gene Symbol: Map3k1
• Gene Name: mitogen-activated protein kinase kinase kinase 1
• Gene Aliases: MAPKKK1, MEKK1, Mekk
• Chromosome Location: Chr.13: 111746433 - 111818269 on Build GRCm38
• UniGene ID: Mm.15918
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Map3k1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_011945.2	NP_036075.2	2	571
GenBank mRNA	AB014614.1	-	2	548
	AF117340.1	-	2	571

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053887, XM_006231926, JQ013733, U48596.

Gene Ontology Categories:

Process(es)

MAPK cascade
epithelial cell morphogenesis
protein phosphorylation
transforming growth factor beta receptor signaling pathway
JNK cascade
activation of JNKK activity
activation of JUN kinase activity
regulation of mitotic cell cycle
apoptotic mitochondrial changes
phosphorylation
protein ubiquitination
regulation of cell migration
positive regulation of actin filament polymerization
wound healing
regulation of apoptotic process
camera-type eye development
eyelid development in camera-type eye

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
JUN kinase kinase kinase activity
MAP kinase kinase kinase activity
ubiquitin-protein transferase activity
protein binding
ATP binding
zinc ion binding
JUN kinase binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding
mitogen-activated protein kinase kinase binding
sphingolipid binding
metal ion binding
mitogen-activated protein kinase binding