189016

• Gene Symbol: Thra
• Gene Name: thyroid hormone receptor alpha
• Gene Aliases: 6430529J03Rik, AW259572, Erba, Nr1a1, Rvr, T3R[a], T3Ralpha, Thra1, Thra2
• Chromosome Location: Chr.11: 98741873 - 98765111 on Build GRCm38
• UniGene ID: Mm.265917
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Thra
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_178060.3	NP_835161.1	3, 4	551
GenBank mRNA	AK078233.1	-	3, 4	551
	AK082121.1	-	3, 4	615
	AK192370.1	-	2, 3	214
	BC046795.1	-		523	5717946
	X07750.1	-	2, 3	121
	X07751.1	-		121
	X07752.1	-		121
	X51983.1	-	2, 3	125

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_199334, NM_003250, NM_001190918, NM_001190919, J03239, and others.
This siRNA also targets the following transcripts in Rat: NM_001017960, NM_031134, X07409, CB580585, M18028, and others.

Gene Ontology Categories:

Process(es)

cartilage condensation
ossification
regulation of thyroid hormone mediated signaling pathway
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
learning or memory
regulation of heart contraction
female courtship behavior
response to cold
hormone-mediated signaling pathway
organ morphogenesis
positive regulation of myotube differentiation
negative regulation of RNA polymerase II transcriptional preinitiation complex assembly
erythrocyte differentiation
intracellular receptor signaling pathway
thyroid gland development
regulation of myeloid cell apoptotic process
cytoplasmic sequestering of transcription factor
steroid hormone mediated signaling pathway
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of transcription, DNA-templated
positive regulation of female receptivity
positive regulation of transcription from RNA polymerase II promoter
regulation of lipid catabolic process
Type I pneumocyte differentiation
negative regulation of DNA-templated transcription, initiation

Function(s)

steroid receptor RNA activator RNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
steroid hormone receptor activity
single-stranded RNA binding
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
thyroid hormone receptor activity
protein binding
transcription factor binding
zinc ion binding
TBP-class protein binding
protein domain specific binding
chromatin DNA binding
protein complex binding
protein homodimerization activity
sequence-specific DNA binding
transcription regulatory region DNA binding
intronic transcription regulatory region DNA binding
metal ion binding
protein heterodimerization activity
protein dimerization activity
thyroid hormone binding