19192

• Gene Symbol: PICALM
• Gene Name: phosphatidylinositol binding clathrin assembly protein
• Gene Aliases: CALM, CLTH, LAP
• Chromosome Location: Chr.11: 85957171 - 86069881 on Build GRCh38
• UniGene ID: Hs.163893
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PICALM
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001008660.2	NP_001008660.1	7	1022
	NM_001206946.1	NP_001193875.1	7	1022
	NM_001206947.1	NP_001193876.1	7	737
	NM_007166.3	NP_009097.2	7	1022
	XM_005274322.2	XP_005274379.1	7	1006
	XM_005274323.2	XP_005274380.1	7	1006
	XM_005274324.2	XP_005274381.1	7	1006
	XM_005274325.2	XP_005274382.1	7	1006
	XM_005274326.2	XP_005274383.1	7	1006
	XM_005274327.2	XP_005274384.1	7	1006
	XM_005274328.2	XP_005274385.1	7	1006
	XM_005274329.3	XP_005274386.1	7	1006
	XM_005274330.2	XP_005274387.1	7	1006
	XM_005274331.2	XP_005274388.1	7	1006
	XM_005274332.2	XP_005274389.1	7	1006
	XM_005274333.2	XP_005274390.1	7	1006
	XM_005274334.2	XP_005274391.1	7	1006
	XM_005274335.2	XP_005274392.1	7	1006
	XM_005274336.2	XP_005274393.1	7	1006
	XM_005274337.2	XP_005274394.1	7	1006
	XM_005274340.2	XP_005274397.1	7	1006
	XM_006718699.2	XP_006718762.1	7	1006
	XM_006718700.2	XP_006718763.1	7	1006
	XM_006718701.3	XP_006718764.1	7	1006
	XM_011545293.1	XP_011543595.1	7	1006
	XM_017018381.1	XP_016873870.1	7	1006
	XM_017018382.1	XP_016873871.1	7	1006
	XM_017018383.1	XP_016873872.1	7	1006
	XM_017018384.1	XP_016873873.1	7	1006
	XM_017018385.1	XP_016873874.1	7	1006
	XM_017018386.1	XP_016873875.1	7	1006
	XM_017018387.1	XP_016873876.1	7	1006
	XM_017018388.1	XP_016873877.1	7	1006
GenBank mRNA	AB210017.1	-	7	1022
	AB451308.1	-	7	705
	AK291414.1	-	8	889
	AK300275.1	-	7	714
	BC048259.1	-	7	783	5537605
	BC064357.1	-	7	984	5112878
	BC073961.1	-	7	858	6183858
	U45976.1	-	7	852

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053554, XM_006229676, XM_006229674, XM_006229681, XM_006229679, and others.
This siRNA also targets the following transcripts in Mouse: NM_001252521, NM_001252524, NM_001252523, NM_146194, NM_001252520, and others.

Gene Ontology Categories:

Process(es)

protein complex assembly
receptor-mediated endocytosis
cell proliferation
negative regulation of gene expression
synaptic vesicle maturation
vesicle-mediated transport
endosomal transport
regulation of endocytosis
receptor internalization
regulation of protein localization
cargo loading into vesicle
positive regulation of transcription, DNA-templated
negative regulation of receptor-mediated endocytosis
clathrin coat assembly
iron ion homeostasis
clathrin-mediated endocytosis
iron ion import into cell
cell-cell adhesion
positive regulation of neuron death
positive regulation of beta-amyloid formation
regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process

Function(s)

protein binding
1-phosphatidylinositol binding
clathrin binding
clathrin heavy chain binding
clathrin adaptor activity
cadherin binding involved in cell-cell adhesion