194999

• Gene Symbol: Tgfbr2
• Gene Name: transforming growth factor, beta receptor 2
• Gene Aliases: TGF-beta 2, Tgfbr2T
• Chromosome Location: Chr.8: 124310288 - 124399345 on Build Rnor_6.0
• UniGene ID: Rn.9954
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Tgfbr2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_031132.3	NP_112394.3	2	397
	XM_008766690.1	XP_008764912.1	3	953
GenBank mRNA	GU067683.1	-	2	146
	L09653.1	-	2	204
	S67770.1	-	2	397

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_009371, NM_029575, AK159327, AK148167, AK090393, and others.

Gene Ontology Categories:

Process(es)

patterning of blood vessels
vasculogenesis
response to hypoxia
in utero embryonic development
positive regulation of mesenchymal cell proliferation
lens development in camera-type eye
positive regulation of tolerance induction to self antigen
positive regulation of B cell tolerance induction
positive regulation of T cell tolerance induction
growth plate cartilage development
growth plate cartilage chondrocyte growth
protein phosphorylation
receptor-mediated endocytosis
apoptotic process
transmembrane receptor protein serine/threonine kinase signaling pathway
transforming growth factor beta receptor signaling pathway
common-partner SMAD protein phosphorylation
smoothened signaling pathway
gastrulation
brain development
heart development
embryo implantation
aging
response to nutrient
negative regulation of cell proliferation
response to mechanical stimulus
response to glucose
organ morphogenesis
response to organic substance
regulation of gene expression
positive regulation of epithelial cell migration
response to organic cyclic compound
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
signal transduction by protein phosphorylation
lung development
organ regeneration
activation of protein kinase activity
embryonic hemopoiesis
wound healing
regulation of cell proliferation
response to drug
myeloid dendritic cell differentiation
positive regulation of skeletal muscle tissue regeneration
response to estrogen
positive regulation of angiogenesis
response to steroid hormone
digestive tract development
positive regulation of smooth muscle cell proliferation
embryonic cranial skeleton morphogenesis
positive regulation of NK T cell differentiation
cartilage development
palate development
negative regulation of cardiac muscle cell proliferation
pathway-restricted SMAD protein phosphorylation
lung morphogenesis
bronchus development
bronchus morphogenesis
trachea morphogenesis
trachea formation
mammary gland morphogenesis
lung lobe morphogenesis
response to cholesterol
lens fiber cell apoptotic process
positive regulation of reactive oxygen species metabolic process

Function(s)

transmembrane receptor protein serine/threonine kinase activity
receptor signaling protein serine/threonine kinase activity
transforming growth factor beta-activated receptor activity
transforming growth factor beta receptor activity, type II
protein binding
ATP binding
glycosaminoglycan binding
mitogen-activated protein kinase kinase kinase binding
type I transforming growth factor beta receptor binding
type III transforming growth factor beta receptor binding
protein homodimerization activity
SMAD binding
metal ion binding
protein heterodimerization activity
transforming growth factor beta binding