195597

• Gene Symbol: Picalm
• Gene Name: phosphatidylinositol binding clathrin assembly protein
• Gene Aliases: Calm
• Chromosome Location: Chr.1: 154377234 - 154458922 on Build Rnor_6.0
• UniGene ID: Rn.24871
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Picalm
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_053554.2	NP_446006.1	17	1695
	XM_006229669.2	XP_006229731.1	17	2001
	XM_006229670.2	XP_006229732.1	17	1986
	XM_006229671.2	XP_006229733.1	17	1981
	XM_006229672.2	XP_006229734.1	17	2001
	XM_006229673.2	XP_006229735.1	17	1986
	XM_006229674.2	XP_006229736.1	17	1980
	XM_006229675.2	XP_006229737.1	17	1965
	XM_006229676.2	XP_006229738.1	17	2000
	XM_006229677.2	XP_006229739.1	17	2000
	XM_006229678.2	XP_006229740.1	17	1985
	XM_006229679.2	XP_006229741.1	16	1850
	XM_006229680.2	XP_006229742.1	16	1835
	XM_006229681.2	XP_006229743.1	16	1850
	XM_006229682.2	XP_006229744.1	16	1835
	XM_006229683.2	XP_006229745.1	16	1850
	XM_006229684.2	XP_006229746.1	16	1835
	XM_006229685.2	XP_006229747.1	16	1835
GenBank mRNA	AF041373.1	-	16	1567
	AF041374.1	-	17	1696
	AY699717.1	-	16	1542
	AY706215.1	-	16	1557
	AY724477.1	-	16	1560
	BC100142.1	-	17	1756	7456159

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001008660, NM_001206946, NM_007166, NM_001206947, BC073961, and others.
This siRNA also targets the following transcripts in Mouse: NM_001252521, NM_001252524, NM_001252523, NM_146194, NM_001252520, and others.

Gene Ontology Categories:

Process(es)

receptor-mediated endocytosis
axonogenesis
cell proliferation
negative regulation of gene expression
synaptic vesicle maturation
vesicle-mediated transport
endosomal transport
hemopoiesis
regulation of endocytosis
receptor internalization
regulation of protein localization
cargo loading into vesicle
positive regulation of transcription, DNA-templated
negative regulation of receptor-mediated endocytosis
clathrin coat assembly
dendrite morphogenesis
regulation of protein transport
iron ion homeostasis
clathrin-mediated endocytosis
iron ion import into cell
positive regulation of neuron death
positive regulation of beta-amyloid formation
regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process

Function(s)

protein binding
1-phosphatidylinositol binding
SH3 domain binding
clathrin binding
clathrin heavy chain binding
clathrin adaptor activity
identical protein binding