197134

• Gene Symbol: Jak3
• Gene Name: Janus kinase 3
• Gene Aliases: RATJAK3
• Chromosome Location: Chr.16: 20107468 - 20120678 on Build Rnor_6.0
• UniGene ID: Rn.11159
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Jak3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_012855.2	NP_036987.2	4	458
	XM_008771064.1	XP_008769286.1	4	1556
GenBank mRNA	D28508.1	-	4	458

More Information

Gene Ontology Categories:

Process(es)

negative regulation of dendritic cell cytokine production
inflammatory response
enzyme linked receptor protein signaling pathway
transmembrane receptor protein tyrosine kinase signaling pathway
positive regulation of cytosolic calcium ion concentration
cell migration
peptidyl-tyrosine phosphorylation
cytokine-mediated signaling pathway
B cell differentiation
erythrocyte differentiation
negative regulation of interleukin-10 production
negative regulation of interleukin-12 production
intracellular signal transduction
interleukin-4-mediated signaling pathway
peptidyl-tyrosine autophosphorylation
positive regulation of T cell proliferation
positive regulation of activated T cell proliferation
tyrosine phosphorylation of Stat5 protein
regulation of apoptotic process
T cell homeostasis
innate immune response
negative regulation of FasL biosynthetic process
negative regulation of T-helper 1 cell differentiation
positive regulation of transcription from RNA polymerase II promoter
protein autophosphorylation
positive regulation of immune response
negative regulation of T cell activation
positive regulation of calcium ion transport
regulation of T cell apoptotic process
negative regulation of thymocyte apoptotic process
response to interleukin-4
positive regulation of dendritic cell apoptotic process
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
ATP binding
transcription factor binding
protein phosphatase binding
hormone receptor binding