197462

• Gene Symbol: Msx2
• Gene Name: msh homeobox 2
• Gene Aliases: -
• Chromosome Location: Chr.17: 11683862 - 11689527 on Build Rnor_6.0
• UniGene ID: Rn.10414
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Msx2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_012982.3	NP_037114.2	2	538
GenBank mRNA	BF414483.1	-	2	311

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_013601, X59252, BC141132, AK131974, AK133846.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
ossification
osteoblast differentiation
chondrocyte development
osteoblast development
outflow tract septum morphogenesis
outflow tract morphogenesis
epithelial to mesenchymal transition involved in endocardial cushion formation
endochondral bone growth
transcription from RNA polymerase II promoter
negative regulation of cell proliferation
anterior/posterior pattern specification
signal transduction involved in regulation of gene expression
embryonic limb morphogenesis
BMP signaling pathway
positive regulation of BMP signaling pathway
negative regulation of CREB transcription factor activity
embryonic forelimb morphogenesis
embryonic hindlimb morphogenesis
wound healing, spreading of epidermal cells
embryonic nail plate morphogenesis
wound healing
odontogenesis
embryonic digit morphogenesis
regulation of apoptotic process
positive regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of fat cell differentiation
negative regulation of keratinocyte differentiation
positive regulation of osteoblast differentiation
negative regulation of transcription, DNA-templated
stem cell differentiation
cartilage development
positive regulation of catagen
bone trabecula formation
bone morphogenesis
frontal suture morphogenesis
branching involved in mammary gland duct morphogenesis
mammary gland epithelium development
BMP signaling pathway involved in heart development
enamel mineralization
cellular response to growth factor stimulus
cellular response to estradiol stimulus
activation of meiosis
negative regulation of transcription regulatory region DNA binding
positive regulation of mesenchymal cell apoptotic process

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, transcription factor binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription cofactor activity
transcription factor binding
sequence-specific DNA binding
transcription regulatory region DNA binding