197514

• Gene Symbol: Pik3r1
• Gene Name: phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
• Gene Aliases: PI3KA
• Chromosome Location: Chr.2: 31742326 - 31816385 on Build Rnor_6.0
• UniGene ID: Rn.10599
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pik3r1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_013005.1	NP_037137.1	11, 12	1576
	XM_006231868.2	XP_006231930.1	6, 7	1762
	XM_008760659.1	XP_008758881.1	6, 7	3212
GenBank mRNA	D64045.1	-	11, 12	1576
	D64048.1	-	6, 7	766
	D78486.1	-	6, 7	676
	U50412.1	-	6, 7	770

More Information

Gene Ontology Categories:

Process(es)

cellular glucose homeostasis
response to yeast
positive regulation of protein phosphorylation
negative regulation of cell-matrix adhesion
glucose metabolic process
protein phosphorylation
aging
response to nutrient
insulin receptor signaling pathway
extrinsic apoptotic signaling pathway via death domain receptors
intrinsic apoptotic signaling pathway in response to DNA damage
response to fructose
response to iron(II) ion
negative regulation of heart rate
positive regulation of gene expression
negative regulation of muscle cell apoptotic process
phosphatidylinositol 3-kinase signaling
protein transport
negative regulation of cell-cell adhesion
B cell differentiation
positive regulation of cell migration
response to estradiol
response to progesterone
positive regulation of tumor necrosis factor production
response to insulin
cellular response to insulin stimulus
positive regulation of RNA splicing
response to testosterone
cellular response to UV
response to endoplasmic reticulum stress
phosphatidylinositol-3-phosphate biosynthetic process
response to drug
positive regulation of transcription factor import into nucleus
negative regulation of apoptotic process
response to amino acid
regulation of phosphatidylinositol 3-kinase activity
response to ethanol
positive regulation of myoblast differentiation
negative regulation of osteoclast differentiation
negative regulation of blood pressure
negative regulation of proteolysis
positive regulation of transcription from RNA polymerase II promoter
phosphatidylinositol phosphorylation
insulin-like growth factor receptor signaling pathway
negative regulation of smooth muscle cell proliferation
protein stabilization
response to glucocorticoid
NFAT protein import into nucleus
response to cAMP
growth hormone receptor signaling pathway
response to fatty acid
response to growth factor
cellular response to fatty acid
response to dexamethasone
positive regulation of endoplasmic reticulum unfolded protein response

Function(s)

receptor binding
insulin receptor binding
insulin-like growth factor receptor binding
platelet-derived growth factor receptor binding
neurotrophin TRKA receptor binding
protein binding
calmodulin binding
protein C-terminus binding
transcription factor binding
1-phosphatidylinositol-3-kinase activity
protein kinase binding
protein phosphatase binding
protein domain specific binding
estrogen receptor binding
receptor tyrosine kinase binding
ubiquitin protein ligase binding
phosphatidylinositol 3-kinase regulator activity
ErbB-3 class receptor binding
phosphatidylinositol 3-kinase binding
insulin binding
insulin receptor substrate binding
1-phosphatidylinositol-3-kinase regulator activity
ATPase binding
phosphoprotein binding