198960

• Gene Symbol: Grik2
• Gene Name: glutamate receptor, ionotropic, kainate 2
• Gene Aliases: GluK2, GluR6
• Chromosome Location: Chr.20: 53791428 - 54517691 on Build Rnor_6.0
• UniGene ID: Rn.87696
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Grik2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_019309.2	NP_062182.1	2, 3	559
GenBank mRNA	Z11548.1	-		579
	Z11715.1	-	2, 3	357

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_001111268, NM_010349, BC131640, BC131639, X66117, and others.

Gene Ontology Categories:

Process(es)

behavioral fear response
cellular calcium ion homeostasis
intracellular protein transport
signal transduction
chemical synaptic transmission
neuronal action potential
ion transmembrane transport
ionotropic glutamate receptor signaling pathway
synaptic transmission, glutamatergic
regulation of membrane potential
receptor clustering
negative regulation of neuron apoptotic process
positive regulation of neuron apoptotic process
regulation of JNK cascade
regulation of long-term neuronal synaptic plasticity
regulation of short-term neuronal synaptic plasticity
modulation of synaptic transmission
positive regulation of synaptic transmission
neuron apoptotic process
negative regulation of synaptic transmission, glutamatergic
excitatory postsynaptic potential
inhibitory postsynaptic potential

Function(s)

ionotropic glutamate receptor activity
extracellular-glutamate-gated ion channel activity
protein binding
glutamate receptor activity
kainate selective glutamate receptor activity
PDZ domain binding
ubiquitin conjugating enzyme binding
ubiquitin protein ligase binding
identical protein binding
protein homodimerization activity