199876

• Gene Symbol: Edn1
• Gene Name: endothelin 1
• Gene Aliases: Et1
• Chromosome Location: Chr.17: 22137324 - 22143324 on Build Rnor_6.0
• UniGene ID: Rn.10918
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Edn1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_012548.2	NP_036680.1	3	473
GenBank mRNA	AF122903.1	-	1	19
	M64711.1	-	3	468

More Information

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
skeletal system development
prostaglandin biosynthetic process
patterning of blood vessels
response to hypoxia
in utero embryonic development
histamine secretion
regulation of systemic arterial blood pressure by endothelin
regulation of pH
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
protein kinase C-activating G-protein coupled receptor signaling pathway
cell-cell signaling
heart development
respiratory gaseous exchange
body fluid secretion
regulation of blood pressure
positive regulation of cell proliferation
dorsal/ventral pattern formation
response to ozone
multicellular organism aging
positive regulation of heart rate
positive regulation of cardiac muscle hypertrophy
positive regulation of receptor biosynthetic process
neural crest cell development
phosphatidylinositol 3-kinase signaling
response to activity
artery smooth muscle contraction
vein smooth muscle contraction
glucose transport
cell growth
regulation of vasoconstriction
sensory perception of pain
calcium-mediated signaling
peptide hormone secretion
nitric oxide transport
positive regulation of cell migration
neutrophil chemotaxis
negative regulation of cAMP biosynthetic process
phospholipase D-activating G-protein coupled receptor signaling pathway
negative regulation of cellular protein metabolic process
positive regulation of prostaglandin secretion
response to lipopolysaccharide
response to testosterone
negative regulation of smooth muscle cell apoptotic process
response to prostaglandin F
response to nicotine
intracellular signal transduction
cellular response to drug
positive regulation of urine volume
positive regulation of renal sodium excretion
response to muscle stretch
epithelial fluid transport
vasoconstriction
protein kinase C deactivation
middle ear morphogenesis
positive regulation of odontogenesis
response to drug
superoxide anion generation
rhythmic excitation
response to amino acid
positive regulation of MAP kinase activity
positive regulation of JUN kinase activity
response to leptin
positive regulation of cell size
positive regulation of mitotic nuclear division
positive regulation of transcription from RNA polymerase II promoter
positive regulation of smooth muscle contraction
positive regulation of hormone secretion
negative regulation of hormone secretion
inositol phosphate-mediated signaling
blood vessel morphogenesis
positive regulation of smooth muscle cell proliferation
cartilage development
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
negative regulation of nitric-oxide synthase biosynthetic process
membrane depolarization
regulation of sensory perception of pain
maternal process involved in parturition
positive regulation of sarcomere organization
positive regulation of prostaglandin-endoperoxide synthase activity
cellular response to calcium ion
cellular response to interferon-gamma
cellular response to interleukin-1
cellular response to tumor necrosis factor
cellular response to peptide hormone stimulus
cellular response to glucocorticoid stimulus
cellular response to mineralocorticoid stimulus
cellular response to fatty acid
cellular response to hypoxia
response to dexamethasone
response to transforming growth factor beta
cellular response to transforming growth factor beta stimulus
positive regulation of neutrophil chemotaxis
response to salt

Function(s)

receptor binding
cytokine activity
hormone activity
endothelin A receptor binding
endothelin B receptor binding