200644

• Gene Symbol: Pde4d
• Gene Name: phosphodiesterase 4D, cAMP-specific
• Gene Aliases: -
• Chromosome Location: Chr.2: 40219999 - 41468551 on Build Rnor_6.0
• UniGene ID: Rn.163460
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pde4d
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001113328.1	NP_001106799.1	2	531
	NM_001113329.1	NP_001106800.1	3	446
	NM_001113332.1	NP_001106803.1	2	383
	NM_001113334.1	NP_001106805.1	2	220
	NM_017032.1	NP_058728.1	2	138
	XM_008760721.1	XP_008758943.1	2	1539
GenBank mRNA	AF031373.1	-	2	531
	AF536979.1	-	3	446
	AY388961.1	-	2	156
	EF102484.1	-	2	383
	EF121818.1	-	2	220
	U09457.1	-	2	138

More Information

Gene Ontology Categories:

Process(es)

regulation of heart rate
cAMP catabolic process
smooth muscle contraction
aging
memory
regulation of G-protein coupled receptor protein signaling pathway
regulation of receptor activity
regulation of protein kinase A signaling
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
positive regulation of smooth muscle cell migration
lung development
neutrophil chemotaxis
positive regulation of interferon-gamma production
positive regulation of interleukin-2 production
positive regulation of interleukin-5 production
negative regulation of peptidyl-serine phosphorylation
multicellular organism growth
cellular protein complex assembly
negative regulation of heart contraction
positive regulation of smooth muscle cell proliferation
T cell receptor signaling pathway
leukocyte migration
regulation of ryanodine-sensitive calcium-release channel activity
establishment of endothelial barrier
cellular response to lipopolysaccharide
cellular response to cAMP
cellular response to epinephrine stimulus
adrenergic receptor signaling pathway
regulation of cardiac muscle cell contraction
adrenergic receptor signaling pathway involved in positive regulation of heart rate
negative regulation of relaxation of cardiac muscle

Function(s)

cyclic-nucleotide phosphodiesterase activity
3',5'-cyclic-nucleotide phosphodiesterase activity
3',5'-cyclic-AMP phosphodiesterase activity
protein binding
drug binding
SH3 domain binding
enzyme binding
protein domain specific binding
cAMP binding
ubiquitin protein ligase binding
beta-2 adrenergic receptor binding
ion channel binding
metal ion binding
ATPase binding
scaffold protein binding