213354

• Gene Symbol: UBE3A
• Gene Name: ubiquitin protein ligase E3A
• Gene Aliases: ANCR, AS, E6-AP, EPVE6AP, HPVE6A
• Chromosome Location: Chr.15: 25337234 - 25439086 on Build GRCh38
• UniGene ID: Hs.598862
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: UBE3A
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000462.3	NP_000453.2	7	1339
	NM_130838.1	NP_570853.1	3	554
	NM_130839.2	NP_570854.1	6	1274
	XM_005268267.4	XP_005268324.1	8	1641
	XM_005268268.4	XP_005268325.1	7	1528
	XM_005268269.4	XP_005268326.1	8	1372
	XM_005268270.4	XP_005268327.1	7	1329
	XM_005268271.4	XP_005268328.1	4	1148
	XM_006720675.3	XP_006720738.1	8	1593
	XM_006720676.3	XP_006720739.1	5	838
	XM_011521994.2	XP_011520296.1	8	1530
	XM_011521995.2	XP_011520297.1	8	1204
	XM_017022544.1	XP_016878033.1	9	1566
	XM_017022545.1	XP_016878034.1	8	1525
	XM_017022546.1	XP_016878035.1	8	1433
	XM_017022547.1	XP_016878036.1	7	1465
	XM_017022548.1	XP_016878037.1	7	1460
	XM_017022549.1	XP_016878038.1	7	1267
	XM_017022550.1	XP_016878039.1	7	1419
	XM_017022551.1	XP_016878040.1	8	1470
	XM_017022552.1	XP_016878041.1	8	1160
	XM_017022553.1	XP_016878042.1	8	1475
	XM_017022554.1	XP_016878043.1	4	1479
	XM_017022555.1	XP_016878044.1	6	1248
	XM_017022556.1	XP_016878045.1	7	1397
	XM_017022557.1	XP_016878046.1	6	1332
	XM_017022558.1	XP_016878047.1	7	1528
	XM_017022559.1	XP_016878048.1	4	1148
GenBank mRNA	AB194232.1	-	5	650
	AF273050.1	-	4	609
	AK056239.1	-	6	1242
	AK130491.1	-	2	283
	AK292514.1	-	6	884
	BC002582.2	-	6	1227	3160225
	L07557.1	-	3	549
	U84404.1	-	8	1096
	X98031.1	-	4	579
	X98032.1	-	2	510
	X98033.1	-	4	570

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001191837, XM_008759399, XM_006229313, XM_006229310, XM_008759400, and others.
This siRNA also targets the following transcripts in Mouse: NM_011668, NM_173010, NM_001033962, AK083795, AK029133, and others.

Gene Ontology Categories:

Process(es)

ovarian follicle development
proteolysis
ubiquitin-dependent protein catabolic process
brain development
positive regulation of phosphatidylinositol 3-kinase signaling
viral process
androgen receptor signaling pathway
positive regulation of protein ubiquitination
sperm entry
regulation of circadian rhythm
positive regulation of transcription from RNA polymerase II promoter
protein autoubiquitination
prostate gland growth
protein K48-linked ubiquitination
regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Function(s)

transcription coactivator activity
ubiquitin-protein transferase activity
protein binding
ligase activity
metal ion binding
ubiquitin protein ligase activity