214165

Gene Symbol:

GH2 CSH1 CSH2 GH1

Gene Name:

growth hormone 2

chorionic somatomammotropin hormone 1

chorionic somatomammotropin hormone 2

growth hormone 1

Gene Aliases:

GH-V, GHB2, GHL, GHV, hGH-V

CS-1, CSA, CSMT, GHB3, PL, hCS-1, hCS-A

CS-2, CSB, GHB1, PL, hCS-B

GH, GH-N, GHB5, GHN, IGHD1B, hGH-N

Chromosome Location:

Chr.17: 63880212 - 63881942 on Build GRCh38

Chromosome Location:

Chr.17: 63894908 - 63896661 on Build GRCh38

Chromosome Location:

Chr.17: 63872012 - 63873729 on Build GRCh38

Chromosome Location:

Chr.17: 63917193 - 63918852 on Build GRCh38

UniGene ID:

Hs.406754

Hs.654390

Hs.654515

Hs.655229

Species:

Human

Species Specific ID (Flybase ID):

-

-

-

-

siRNA Details

Gene Symbol: GH2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002059.4	NP_002050.1	5	701
	NM_022556.3	NP_072050.1	5	656
	NM_022557.3	NP_072051.1	4	954
	NM_022558.3	NP_072052.1	5	697
GenBank mRNA	AB451332.1	-	4	515
	AB451477.1	-	4	515
	AF006060.1	-	5	527
	AF006061.1	-	4	556
	BC020760.1	-	5	622	4720475
	CR541902.1	-	4	560
	CR541924.1	-	4	560
	J03756.1	-	4	874
	M38451.1	-	5	572

Gene Symbol: CSH1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001317.5	NP_001308.1	5	710
GenBank mRNA	AK291587.1	-	5	629
	BC002717.2	-	5	603	3631916
	BC005921.1	-	5	622	4043768
	BC020756.1	-	5	678	4769769
	BC057768.1	-	5	622	30337725
	BC062775.1	-	5	626	4604848
	BT006926.1	-	4	560
	J00118.1	-	5	589
	M25118.1	-	1	83
	V00593.1	-	4	412

Gene Symbol: CSH2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_020991.3	NP_066271.1	5	675
	NM_022644.3	NP_072170.1	4	928
	NM_022645.2	NP_072171.1	3	390
GenBank mRNA	BC022044.1	-	5	626	4769046
	BC035965.1	-	5	622	4731880
	BC119748.2	-	5	619	40119242
	V00573.1	-	5	584

Gene Symbol: GH1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000515.4	NP_000506.2	5	636
	NM_022559.3	NP_072053.1	5	591
	NM_022560.3	NP_072054.1	4	516
GenBank mRNA	A00469.1	-	5	599
	AF110644.1	-	5	432
	AF185611.1	-	6	464
	AV753220.1	-	3	456
	AY613431.1	-	5	622
	AY613432.1	-	5	622
	BC062475.1	-	5	556	30393581
	BC075012.2	-	5	587	30915404
	BC075013.2	-	5	587	30915617
	BC090045.1	-	5	603	30394115
	CD108592.1	-	4	482
	V00519.1	-	5	600

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

JAK-STAT cascade involved in growth hormone signaling pathway
positive regulation of receptor internalization
JAK-STAT cascade
positive regulation of activation of JAK2 kinase activity
positive regulation of phosphatidylinositol 3-kinase signaling
glucose transport
response to estradiol
positive regulation of multicellular organism growth
positive regulation of tyrosine phosphorylation of Stat3 protein
positive regulation of tyrosine phosphorylation of Stat5 protein
positive regulation of MAP kinase activity
positive regulation of insulin-like growth factor receptor signaling pathway
positive regulation of JAK-STAT cascade
positive regulation of peptidyl-tyrosine phosphorylation
growth hormone receptor signaling pathway
bone maturation

Function(s)

hormone activity
growth hormone receptor binding
prolactin receptor binding
protein binding
growth factor activity
metal ion binding