214379

• Gene Symbol: PDPK1
• Gene Name: 3-phosphoinositide dependent protein kinase 1
• Gene Aliases: PDK1, PDPK2, PDPK2P, PRO0461
• Chromosome Location: Chr.16: 2537964 - 2603190 on Build GRCh38
• UniGene ID: Hs.459691
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PDPK1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001261816.1	NP_001248745.1	10, 11	1267
	NM_002613.4	NP_002604.1	10, 11	1267
	NM_031268.5	NP_112558.2	7, 8	886
	XM_011522521.2	XP_011520823.1	10, 11	4955
	XM_011522523.2	XP_011520825.1	7, 8	4579
	XM_017023271.1	XP_016878760.1	10, 11	4960
	XM_017023272.1	XP_016878761.1	10, 11	1516
	XM_017023273.1	XP_016878762.1	10, 11	1225
	XM_017023274.1	XP_016878763.1	11, 12	1363
	XM_017023275.1	XP_016878764.1	7, 8	4585
	XM_017023276.1	XP_016878765.1	7, 8	829
	XM_017023277.1	XP_016878766.1	8, 9	927
GenBank mRNA	AB209835.1	-	10, 11	1234
	AF017995.1	-	10, 11	1198
	AK131060.1	-	10, 11	1201
	AK222581.1	-	10, 11	1210
	BC006339.2	-	7, 8	847	4079551
	BC012103.1	-	10, 11	1227	4561371
	BC033494.1	-	7, 8	799	5176294
	CR536517.1	-	10, 11	1118
	Y15056.1	-	10, 11	1197

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

stimulatory C-type lectin receptor signaling pathway
type B pancreatic cell development
transcription, DNA-templated
regulation of transcription, DNA-templated
protein phosphorylation
negative regulation of protein kinase activity
hyperosmotic response
epidermal growth factor receptor signaling pathway
positive regulation of phospholipase activity
regulation of endothelial cell migration
negative regulation of cardiac muscle cell apoptotic process
cell migration
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
calcium-mediated signaling
actin cytoskeleton organization
platelet activation
negative regulation of transforming growth factor beta receptor signaling pathway
T cell costimulation
activation of protein kinase B activity
cellular response to insulin stimulus
negative regulation of toll-like receptor signaling pathway
intracellular signal transduction
Fc-epsilon receptor signaling pathway
regulation of I-kappaB kinase/NF-kappaB signaling
regulation of mast cell degranulation
protein autophosphorylation
phosphatidylinositol-mediated signaling
focal adhesion assembly
T cell receptor signaling pathway
positive regulation of release of sequestered calcium ion into cytosol
cellular response to epidermal growth factor stimulus
positive regulation of establishment of protein localization to plasma membrane
extrinsic apoptotic signaling pathway

Function(s)

protein serine/threonine kinase activity
3-phosphoinositide-dependent protein kinase activity
insulin receptor binding
protein binding
ATP binding
phospholipase activator activity
kinase activity
protein kinase binding
phospholipase binding