214504

• Gene Symbol: Map3k7
• Gene Name: mitogen-activated protein kinase kinase kinase 7
• Gene Aliases: B430101B05, C87327, Tak1
• Chromosome Location: Chr.4: 31962296 - 32023470 on Build GRCm38
• UniGene ID: Mm.258589
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Map3k7
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_009316.1	NP_033342.1	17	1922
	NM_172688.3	NP_766276.1	16	1841
GenBank mRNA	AK046565.1	-	16	1807
	AK053911.1	-	16	1827
	AK133642.1	-	10	968
	AK137046.1	-	16	1842
	AK159277.1	-	16	1805
	BC006665.1	-	17	1913	3499247
	D76446.1	-	16	1841

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_003188, NM_145331, NM_145332, NM_145333, AK055901, and others.
This siRNA also targets the following transcripts in Rat: NM_001107920, XM_003750753, XM_006237966, XM_006245614.

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPK activity
angiogenesis
neural tube formation
transcription, DNA-templated
regulation of transcription, DNA-templated
protein phosphorylation
apoptotic process
transforming growth factor beta receptor signaling pathway
I-kappaB phosphorylation
phosphorylation
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of JNK cascade
negative regulation of necroptotic process
negative regulation of ripoptosome assembly involved in necroptotic process
regulation of reactive oxygen species metabolic process
negative regulation of reactive oxygen species metabolic process
negative regulation of apoptotic signaling pathway

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase activity
MAP kinase kinase kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
metal ion binding
scaffold protein binding