214521

• Gene Symbol: Hdac3
• Gene Name: histone deacetylase 3
• Gene Aliases: AW537363
• Chromosome Location: Chr.18: 37936971 - 37955000 on Build GRCm38
• UniGene ID: Mm.20521
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Hdac3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_010411.2	NP_034541.2	14	1200
GenBank mRNA	AF074881.1	-	14	1147
	AF074882.1	-	8	574
	AF098295.1	-	14	1125
	AF125536.1	-	14	1132
	AK037478.1	-		1192
	AK145158.1	-	14	1166
	BC139300.1	-	14	1228	8862322
	BC139301.1	-	14	1228	8862323
	JN651901.1	-	8	848
	JN651902.1	-	7	806
	JN651903.1	-	8	557
	JN651904.1	-	5	402

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053448, AF321131, BC061988.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
positive regulation of protein phosphorylation
transcription, DNA-templated
regulation of transcription, DNA-templated
protein deacetylation
regulation of mitotic cell cycle
chromatin modification
histone deacetylation
regulation of protein stability
positive regulation of TOR signaling
negative regulation of interleukin-1 production
negative regulation of tumor necrosis factor production
circadian regulation of gene expression
regulation of multicellular organism growth
positive regulation of transcription factor import into nucleus
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of neuron apoptotic process
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of JNK cascade
negative regulation of protein export from nucleus
spindle assembly
cellular response to fluid shear stress
positive regulation of type B pancreatic cell apoptotic process
negative regulation of cardiac muscle cell differentiation

Function(s)

DNA binding
chromatin binding
transcription corepressor activity
histone deacetylase activity
protein binding
transcription factor binding
hydrolase activity
enzyme binding
cyclin binding
histone deacetylase activity (H3-K14 specific)
chromatin DNA binding
NAD-dependent histone deacetylase activity (H3-K14 specific)
histone deacetylase activity (H3-K9 specific)
protein deacetylase activity
histone deacetylase activity (H4-K16 specific)
histone deacetylase binding
NAD-dependent histone deacetylase activity (H3-K9 specific)
NAD-dependent histone deacetylase activity (H4-K16 specific)
GTPase binding
NF-kappaB binding
NAD-dependent histone deacetylase activity (H3-K18 specific)