21514

Gene Symbol:

DCLRE1C CLK1 DSTNP2 NME7 RHBDL2 RTCA SMYD5 TACC1 THUMPD2 TRAPPC2 ZYG11A

Gene Name:

DNA cross-link repair 1C

CDC like kinase 1

destrin, actin depolymerizing factor pseudogene 2

NME/NM23 family member 7

rhomboid like 2

RNA 3'-terminal phosphate cyclase

SMYD family member 5

transforming acidic coiled-coil containing protein 1

THUMP domain containing 2

trafficking protein particle complex 2

zyg-11 family member A, cell cycle regulator

Gene Aliases:

A-SCID, DCLREC1C, RS-SCID, SCIDA, SNM1C

CLK, CLK/STY, STY

-

CFAP67, MN23H7, NDK 7, NDK7, nm23-H7

RRP2

RPC, RTC1, RTCD1

NN8-4AG, RAI15, RRG1, ZMYND23

Ga55

C2orf8

MIP2A, SEDL, SEDT, TRAPPC2P1, TRS20, ZNF547L, hYP38334

ZYG11

Chromosome Location:

Chr.10: 14897853 - 14954432 on Build GRCh38

Chromosome Location:

Chr.2: 200853009 - 200864744 on Build GRCh38

Chromosome Location:

Chr.12: 6884682 - 6885786 on Build GRCh38

Chromosome Location:

Chr.1: 169132385 - 169367963 on Build GRCh38

Chromosome Location:

Chr.1: 38885806 - 38941830 on Build GRCh38

Chromosome Location:

Chr.1: 100266158 - 100292769 on Build GRCh38

Chromosome Location:

Chr.2: 73214238 - 73227227 on Build GRCh38

Chromosome Location:

Chr.8: 38728186 - 38853028 on Build GRCh38

Chromosome Location:

Chr.2: 39736060 - 39779276 on Build GRCh38

Chromosome Location:

Chr.X: 13712242 - 13734635 on Build GRCh38

Chromosome Location:

Chr.1: 52842511 - 52894575 on Build GRCh38

UniGene ID:

Hs.655932

Hs.433732

Hs.661103

Hs.706952

Hs.524626

Hs.484222

Hs.631882

Hs.279245

Hs.468254

Hs.592238

Hs.658458

Species:

Human

Species Specific ID (Flybase ID):

-

-

-

-

-

-

-

-

-

-

-

siRNA Details

Gene Symbol: DCLRE1C
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001033855.2	NP_001029027.1	14	5105
	NM_001033857.2	NP_001029029.1	15	5190
	NM_001033858.2	NP_001029030.1	16	5512
	NM_001289076.1	NP_001276005.1	12	4964
	NM_001289077.1	NP_001276006.1	15	5236
	NM_001289078.1	NP_001276007.1	12	4997
	NM_001289079.1	NP_001276008.1	16	5558
	NM_022487.3	NP_071932.2	13	5049
	NR_110297.1		17	5458

Gene Symbol: CLK1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AK025306.1	-	3	2181

Gene Symbol: DSTNP2
Interrogated Sequence		Translated Protein	RNADB ID	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_033796.2			1	867
GenBank mRNA	U72518.1	-	LIT2102 destrin-2 pseudogene	1	867

Gene Symbol: NME7
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AB209049.1	-	7	1314

Gene Symbol: RHBDL2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AW080436.1	-	1	347

Gene Symbol: RTCA
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001130841.1	NP_001124313.1	12	1972
	NM_003729.3	NP_003720.1	11	1933
	XM_005271298.4	XP_005271355.1	11	1930
	XM_005271299.4	XP_005271356.1	11	1919
	XM_017002669.1	XP_016858158.1	11	1676
GenBank mRNA	CA437545.1	-	1	189

Gene Symbol: SMYD5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_017003163.1	XP_016858652.1	1	135

Gene Symbol: TACC1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AK124297.1	-	4	1171

Gene Symbol: THUMPD2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AF380578.1	-	1	494

Gene Symbol: TRAPPC2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001011658.3	NP_001011658.1	6	1139
	NM_001128835.2	NP_001122307.2	6	1133
	NM_014563.5	NP_055378.1	5	997
	XM_011545565.1	XP_011543867.1	7	1207
	XM_011545566.2	XP_011543868.1	6	1063
GenBank mRNA	AK055671.1	-	1	304
	BC016915.1	-	5	960	4432196
	BC052618.1	-	5	960	6581382
	BG033605.1	-		139

Gene Symbol: ZYG11A
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001004339.2	NP_001004339.2	14	3707
	NM_001307931.1	NP_001294860.1	13	2955
	XM_011541480.2	XP_011539782.1	13	3437
	XM_011541481.2	XP_011539783.1	13	3305
	XM_011541482.2	XP_011539784.1	13	3287
	XM_011541483.2	XP_011539785.1	12	3242

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

adaptive immune response
double-strand break repair via nonhomologous end joining
response to ionizing radiation
B cell differentiation
protection from non-homologous end joining at telomere
V(D)J recombination
interstrand cross-link repair
nucleic acid phosphodiester bond hydrolysis
RNA processing
biological_process
methylation
skeletal system development
transcription, DNA-templated
regulation of transcription, DNA-templated
ER to Golgi vesicle-mediated transport
COPII vesicle coating
protein ubiquitination
regulation of ubiquitin-protein transferase activity

Function(s)

single-stranded DNA endodeoxyribonuclease activity
damaged DNA binding
endonuclease activity
protein binding
5'-3' exonuclease activity
5'-3' exodeoxyribonuclease activity
RNA binding
RNA-3'-phosphate cyclase activity
ATP binding
poly(A) RNA binding
molecular_function
methyltransferase activity
metal ion binding
transcription factor binding
ion channel binding
ubiquitin-protein transferase activity