224840

• Gene Symbol: ISCU
• Gene Name: iron-sulfur cluster assembly enzyme
• Gene Aliases: 2310020H20Rik, HML, ISU2, NIFU, NIFUN, hnifU
• Chromosome Location: Chr.12: 108561463 - 108569384 on Build GRCh38
• UniGene ID: Hs.615131
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ISCU
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001301140.1	NP_001288069.1	2	1329
	NM_001301141.1	NP_001288070.1	2	1329
	NM_001320042.1	NP_001306971.1	2	1329
	NM_014301.4	NP_055116.1	3	1425
	NM_213595.3	NP_998760.1	2	1329
	NR_135127.1		3	1425
	XM_011538100.2	XP_011536402.1	3	1425
	XM_011538101.2	XP_011536403.1	2	1329
GenBank mRNA	AK000574.1	-	2	172
	AK022758.1	-	1	1753
	AK057251.1	-	2	1329
	AK293202.1	-	2	182
	AK297862.1	-	2	201
	AY009127.1	-	3	282
	AY009128.1	-	2	186
	BC011906.2	-	2	185	4136262
	BC061903.1	-	2	178	4183674
	BG702203.1	-	2	180
	BI597126.1	-	2	280
	BM423850.1	-	2	175
	BM921073.1	-	2	270
	BP378051.1	-	2	201
	BU602914.1	-	2	190
	DB095495.1	-	2	196
	DB493673.1	-	2	259
	EU329002.1	-	3	282
	U47101.1	-	1	32

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001105936, BC167056.
This siRNA also targets the following transcripts in Mouse: NM_025526, AK039834, AK009021, BC048409, AK009421, and others.

Gene Ontology Categories:

Process(es)

cellular iron ion homeostasis
nitrogen fixation
iron-sulfur cluster assembly
small molecule metabolic process
[2Fe-2S] cluster assembly
protein maturation by iron-sulfur cluster transfer

Function(s)

iron ion binding
protein binding
ferrous iron binding
protein complex scaffold
iron-sulfur transferase activity
2 iron, 2 sulfur cluster binding
4 iron, 4 sulfur cluster binding