227849

Gene Symbol:

HLA-DRB1 HLA-DRB4 HLA-DRB5

Gene Name:

major histocompatibility complex, class II, DR beta 1

major histocompatibility complex, class II, DR beta 4

major histocompatibility complex, class II, DR beta 5

Gene Aliases:

DRB1, DRw10, HLA-DR1B, HLA-DRB, SS1

DR-4, DR4, DRB4, HLA-DR4B

HLA-DRB

Chromosome Location:

Chr.6: 32578769 - 32589836 on Build GRCh38

Chromosome Location:

-

Chromosome Location:

Chr.6: 32517343 - 32530316 on Build GRCh38

UniGene ID:

Hs.534322

Hs.534322

Hs.485130

Species:

Human

Species Specific ID (Flybase ID):

-

-

-

siRNA Details

Gene Symbol: HLA-DRB1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001243965.1	NP_001230894.1	2	216
GenBank mRNA	AF017441.1	-	1	35
	AJ297583.1	-	2	122
	AJ297587.1	-	2	122
	AJ697892.1	-	2	131
	AJ697893.1	-	2	131
	AY961065.1	-	2	122
	AY961066.1	-	2	122
	BC007920.2	-	2	168	4309837
	BC008403.1	-	2	185	4272571
	BC031023.1	-	2	185	4695321
	DB246210.1	-	2	226
	L76133.1	-	2	162
	M11867.1	-	2	151
	M25265.1	-	1	35
	M25266.1	-	1	35
	U37582.1	-	1	35
	U65585.1	-	2	162
	U95817.1	-	1	35
	X00699.1	-	2	157

Gene Symbol: HLA-DRB4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AK225683.1	-	2	185
	AK225690.1	-	2	185
	AK291499.1	-	2	185
	AK293020.1	-	2	226
	AY961064.1	-	2	122
	AY961067.1	-	2	122
	AY961070.2	-	2	122
	M59803.1	-	1	35
	U17379.1	-	1	49
	U29342.1	-	1	35
	U35375.1	-	1	35
	U35729.1	-	1	35
	U37433.1	-	1	35
	U47028.1	-	1	35

Gene Symbol: HLA-DRB5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AB062112.2	-	2	166
	AF490771.1	-	2	103
	AJ297582.1	-	2	122
	AJ580838.1	-	1	22
	M17379.1	-	1	35
	M17382.1	-	1	35
	M17383.1	-	1	35
	M27689.1	-	1	35
	M59798.1	-	1	35
	U17381.1	-	2	49
	U95818.1	-		14
	X99895.1	-	2	129

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

polysaccharide assembly with MHC class II protein complex
antigen processing and presentation of exogenous peptide antigen via MHC class II
T cell costimulation
T cell receptor signaling pathway
interferon-gamma-mediated signaling pathway

Function(s)

MHC class II protein complex binding
peptide antigen binding