227851

Gene Symbol:

HLA-DRB1 HLA-DRB4 HLA-DRB5

Gene Name:

major histocompatibility complex, class II, DR beta 1

major histocompatibility complex, class II, DR beta 4

major histocompatibility complex, class II, DR beta 5

Gene Aliases:

DRB1, DRw10, HLA-DR1B, HLA-DRB, SS1

DR-4, DR4, DRB4, HLA-DR4B

HLA-DRB

Chromosome Location:

Chr.6: 32578769 - 32589836 on Build GRCh38

Chromosome Location:

-

Chromosome Location:

Chr.6: 32517343 - 32530316 on Build GRCh38

UniGene ID:

Hs.534322

Hs.534322

Hs.485130

Species:

Human

Species Specific ID (Flybase ID):

-

-

-

siRNA Details

Gene Symbol: HLA-DRB1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001243965.1	NP_001230894.1	3	522
GenBank mRNA	U65585.1	-	3	468
	X00699.1	-	3	463

Gene Symbol: HLA-DRB4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AK291499.1	-	3	491
	AY961064.1	-	3	428
	AY961067.1	-	3	428
	AY961070.2	-	3	428

Gene Symbol: HLA-DRB5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	M17379.1	-	2	341
	X99895.1	-	3	435

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

polysaccharide assembly with MHC class II protein complex
antigen processing and presentation of exogenous peptide antigen via MHC class II
T cell costimulation
T cell receptor signaling pathway
interferon-gamma-mediated signaling pathway

Function(s)

MHC class II protein complex binding
peptide antigen binding