228935

• Gene Symbol: NPM1
• Gene Name: nucleophosmin
• Gene Aliases: B23, NPM
• Chromosome Location: Chr.5: 171387648 - 171410900 on Build GRCh38
• UniGene ID: Hs.557550
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NPM1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001037738.2	NP_001032827.1	9, 10	1013
	XM_005265920.3	XP_005265977.1	8, 9	982
GenBank mRNA	AB042278.1	-	9, 10	768
	AK000472.1	-	7, 8	576
	BC107754.1	-	9, 10	869	6736004

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_008767546, FQ229578, FQ230103, FQ229552, J04943, and others.
This siRNA also targets the following transcripts in Mouse: NM_001252261, AK184065, BC090843, AK005420, AK088923.

Gene Ontology Categories:

Process(es)

DNA repair
nucleosome assembly
intracellular protein transport
nucleocytoplasmic transport
response to stress
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
centrosome cycle
signal transduction
cell aging
protein localization
positive regulation of cell proliferation
negative regulation of cell proliferation
negative regulation of centrosome duplication
viral process
regulation of endodeoxyribonuclease activity
CENP-A containing nucleosome assembly
ribosome assembly
negative regulation of apoptotic process
negative regulation of protein kinase activity by regulation of protein phosphorylation
positive regulation of translation
positive regulation of transcription, DNA-templated
regulation of centriole replication
positive regulation of NF-kappaB transcription factor activity
protein oligomerization
regulation of endoribonuclease activity
regulation of eIF2 alpha phosphorylation by dsRNA
positive regulation of cell cycle G2/M phase transition

Function(s)

transcription coactivator activity
RNA binding
protein kinase inhibitor activity
protein binding
protein kinase binding
Tat protein binding
histone binding
protein homodimerization activity
ribosomal large subunit binding
ribosomal small subunit binding
poly(A) RNA binding
protein heterodimerization activity
NF-kappaB binding
unfolded protein binding