23216

Gene Symbol:

RTEL1 RTEL1-TNFRSF6B

Gene Name:

regulator of telomere elongation helicase 1

RTEL1-TNFRSF6B readthrough (NMD candidate)

Gene Aliases:

C20orf41, DKCA4, DKCB5, NHL, PFBMFT3, RTEL

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Chromosome Location:

Chr.20: 63657810 - 63696253 on Build GRCh38

Chromosome Location:

Chr.20: 63657810 - 63698698 on Build GRCh38

UniGene ID:

Hs.745057

Hs.745057

Species:

Human

Species Specific ID (Flybase ID):

-

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siRNA Details

Gene Symbol: RTEL1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001283009.1	NP_001269938.1	26	3195
	NM_001283010.1	NP_001269939.1	25	2916
	NM_016434.3	NP_057518.1	26	3195
	NM_032957.4	NP_116575.3	26	3267
GenBank mRNA	AF217795.1	-	26	3195
	AK000485.1	-	2	398
	AK299332.1	-	26	2690
	AK302508.1	-	26	2786
	AK304798.1	-	25	2412
	AL080127.1	-	3	248
	JX119186.1	-	25	2368

Gene Symbol: RTEL1-TNFRSF6B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_037882.1		26	3195

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

telomere maintenance
strand displacement
DNA repair
regulation of double-strand break repair via homologous recombination
replication fork processing
positive regulation of telomere maintenance
DNA duplex unwinding
telomere maintenance in response to DNA damage
telomeric loop disassembly
mitotic telomere maintenance via semi-conservative replication
positive regulation of telomere capping
positive regulation of telomere maintenance via telomere lengthening
negative regulation of t-circle formation
negative regulation of telomere maintenance in response to DNA damage
positive regulation of telomeric loop disassembly

Function(s)

DNA binding
ATP-dependent DNA helicase activity
protein binding
ATP binding
metal ion binding
4 iron, 4 sulfur cluster binding