2346

• Gene Symbol: APOA1
• Gene Name: apolipoprotein A1
• Gene Aliases: apo(a)
• Chromosome Location: Chr.11: 116835751 - 116837950 on Build GRCh38
• UniGene ID: Hs.93194
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: APOA1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000039.2	NP_000030.1	4	698
	NM_001318017.1	NP_001304946.1	4	411
	NM_001318018.1	NP_001304947.1	4	403
	NM_001318021.1	NP_001304950.1	4	654
GenBank mRNA	A14829.1	-	3	351
	A15879.1	-	2	260
	AK292231.1	-	4	372
	AL531353.3	-	4	403
	AL557908.3	-	4	411
	BC005380.1	-	4	370	3934992
	BC110286.1	-	4	393	5164525
	BU600916.1	-	4	329
	M11791.1	-	3	332
	M27875.1	-	3	351
	M29068.1	-	2	278
	X02162.1	-	4	418

More Information

Gene Ontology Categories:

Process(es)

retinoid metabolic process
regulation of protein phosphorylation
endothelial cell proliferation
platelet degranulation
negative regulation of cytokine secretion involved in immune response
phospholipid metabolic process
phosphatidylcholine biosynthetic process
cholesterol biosynthetic process
receptor-mediated endocytosis
transforming growth factor beta receptor signaling pathway
G-protein coupled receptor signaling pathway
integrin-mediated signaling pathway
response to nutrient
cholesterol metabolic process
glucocorticoid metabolic process
negative regulation of tumor necrosis factor-mediated signaling pathway
positive regulation of cholesterol esterification
positive regulation of triglyceride catabolic process
negative regulation of very-low-density lipoprotein particle remodeling
peripheral nervous system axon regeneration
protein oxidation
peptidyl-methionine modification
triglyceride catabolic process
lipid storage
regulation of intestinal cholesterol absorption
cholesterol transport
adrenal gland development
organ regeneration
neuron projection regeneration
regulation of Cdc42 protein signal transduction
cholesterol efflux
phospholipid efflux
negative regulation of heterotypic cell-cell adhesion
high-density lipoprotein particle remodeling
high-density lipoprotein particle assembly
high-density lipoprotein particle clearance
positive regulation of Rho protein signal transduction
lipoprotein metabolic process
lipoprotein biosynthetic process
response to drug
cholesterol homeostasis
blood vessel endothelial cell migration
response to estrogen
reverse cholesterol transport
cellular protein metabolic process
positive regulation of fatty acid biosynthetic process
negative regulation of interleukin-1 beta secretion
negative regulation of inflammatory response
protein stabilization
negative chemotaxis
positive regulation of lipoprotein lipase activity
vitamin transport
positive regulation of hydrolase activity
positive regulation of stress fiber assembly
transmembrane transport
phospholipid homeostasis
negative regulation of lipase activity
negative regulation of cell adhesion molecule production
negative regulation of response to cytokine stimulus
triglyceride homeostasis
ERK1 and ERK2 cascade
cholesterol import
positive regulation of substrate adhesion-dependent cell spreading

Function(s)

beta-amyloid binding
protein binding
phospholipid binding
phospholipid transporter activity
high-density lipoprotein particle binding
cholesterol binding
cholesterol transporter activity
enzyme binding
phosphatidylcholine binding
apolipoprotein receptor binding
apolipoprotein A-I receptor binding
identical protein binding
chemorepellent activity
lipase inhibitor activity
phosphatidylcholine-sterol O-acyltransferase activator activity
high-density lipoprotein particle receptor binding