235766

• Gene Symbol: SPO11
• Gene Name: SPO11, initiator of meiotic double stranded breaks
• Gene Aliases: CT35, SPATA43, TOPVIA
• Chromosome Location: Chr.20: 57329757 - 57343993 on Build GRCh38
• UniGene ID: Hs.159737
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SPO11
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_012444.2	NP_036576.1	13	1222
	NM_198265.1	NP_937998.1	12	1108
	XM_005260379.3	XP_005260436.1	14	1273
	XM_005260380.3	XP_005260437.1	14	1267
	XM_005260381.3	XP_005260438.1	13	1234
	XM_005260382.4	XP_005260439.1	12	1696
	XM_011528756.2	XP_011527058.1	13	1159
	XM_011528757.2	XP_011527059.1	14	1107
GenBank mRNA	AF149310.1	-	13	1162
	AF169385.1	-	13	1237
	BC033591.1	-	12	1070	5167214

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

DNA catabolic process, endonucleolytic
ovarian follicle development
synaptonemal complex assembly
reciprocal meiotic recombination
male meiosis I
spermatogenesis
spermatid development
female gamete generation
protein localization to chromosome
meiotic telomere clustering
oogenesis

Function(s)

DNA binding
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein binding
ATP binding
metal ion binding