237043

• Gene Symbol: SMAD1
• Gene Name: SMAD family member 1
• Gene Aliases: BSP-1, BSP1, JV4-1, JV41, MADH1, MADR1
• Chromosome Location: Chr.4: 145481306 - 145559176 on Build GRCh38
• UniGene ID: Hs.604588
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SMAD1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001003688.1	NP_001003688.1	6	1366
	NM_005900.2	NP_005891.1	6	1542
	XM_005262992.3	XP_005263049.1	6	1335
	XM_006714217.2	XP_006714280.1	6	1397
	XM_011531961.1	XP_011530263.1	6	1357
	XM_011531962.1	XP_011530264.1	6	1402
	XM_011531963.1	XP_011530265.1	6	1524
	XM_011531964.1	XP_011530266.1	6	1554
GenBank mRNA	AK096624.1	-	2	2877
	AK293055.1	-	6	1668
	BC001878.1	-	6	1467	3546771
	BT007386.1	-	5	1126
	U54826.1	-	6	1366
	U57456.1	-	5	1278
	U59423.1	-	6	1558
	U59912.1	-	6	1367

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

MAPK cascade
ureteric bud development
mesodermal cell fate commitment
osteoblast fate commitment
transcription from RNA polymerase II promoter
inflammatory response
signal transduction
transforming growth factor beta receptor signaling pathway
SMAD protein complex assembly
gamete generation
negative regulation of cell proliferation
embryonic pattern specification
positive regulation of gene expression
BMP signaling pathway
midbrain development
hindbrain development
primary miRNA processing
homeostatic process
positive regulation of osteoblast differentiation
positive regulation of transcription from RNA polymerase II promoter
cartilage development
cardiac muscle cell proliferation
bone development
SMAD protein signal transduction
positive regulation of cartilage development
positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
receptor signaling protein activity
protein binding
protein kinase binding
transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
identical protein binding
protein homodimerization activity
metal ion binding
protein heterodimerization activity
co-SMAD binding
I-SMAD binding