237976

Gene Symbol:

DEFA1 DEFA1B DEFA3

Gene Name:

defensin alpha 1

defensin alpha 1B

defensin alpha 3

Gene Aliases:

DEF1, DEFA2, HNP-1, HP-1, HP1, MRS

HNP-1, HP-1, HP1

DEF3, HNP-3, HNP3, HP-3, HP3

Chromosome Location:

Chr.8: 6977649 - 6980119 on Build GRCh38

Chromosome Location:

Chr.8: 6996766 - 6999202 on Build GRCh38

Chromosome Location:

Chr.8: 7015869 - 7018336 on Build GRCh38

UniGene ID:

Hs.380781

Hs.380781

Hs.654448

Species:

Human

Species Specific ID (Flybase ID):

-

-

-

siRNA Details

Gene Symbol: DEFA1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_004084.3	NP_004075.1	2	173
	XM_011534740.2	XP_011533042.1	3	244
GenBank mRNA	AL036554.2	-	2	176
	BC069423.1	-	2	131	7262694
	BC093791.1	-	2	128	7939636
	BC112188.1	-	2	128	8327656
	M21130.1	-	2	131
	M26602.1	-	2	174
	X52053.1	-	2	153

Gene Symbol: DEFA1B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001042500.1	NP_001035965.1	2	173
	NM_001302265.1	NP_001289194.1	3	217
GenBank mRNA	HY073456.1	-	3	215

Gene Symbol: DEFA3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005217.3	NP_005208.1	2	166
	XM_011534741.2	XP_011533043.1	3	252
GenBank mRNA	BC027917.1	-	2	153	5226993
	BC119706.2	-	2	151	40117146
	M23281.1	-	2	131
	X13621.1	-	2	170

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

innate immune response in mucosa
chemotaxis
immune response
antibacterial humoral response
intracellular estrogen receptor signaling pathway
killing of cells of other organism
innate immune response
defense response to Gram-positive bacterium
defense response to fungus
defense response to virus

Function(s)

molecular_function