240746

• Gene Symbol: CHD8
• Gene Name: chromodomain helicase DNA binding protein 8
• Gene Aliases: AUTS18, HELSNF1
• Chromosome Location: Chr.14: 21385194 - 21437298 on Build GRCh38
• UniGene ID: Hs.530698
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CHD8
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001170629.1	NP_001164100.1	13	2959
	NM_020920.3	NP_065971.2	14	2204
GenBank mRNA	AB046784.3	-	13	2447
	AK122868.1	-	4	569
	AK122910.1	-	14	2151
	CR749315.1	-	14	2149

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_201637, DQ190419.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
in utero embryonic development
transcription, DNA-templated
brain development
covalent chromatin modification
negative regulation of Wnt signaling pathway
DNA duplex unwinding
ATP-dependent chromatin remodeling
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of transcription from RNA polymerase III promoter
digestive tract development
canonical Wnt signaling pathway
negative regulation of canonical Wnt signaling pathway
negative regulation of fibroblast apoptotic process

Function(s)

p53 binding
DNA binding
DNA helicase activity
chromatin binding
protein binding
ATP binding
beta-catenin binding
DNA-dependent ATPase activity
methylated histone binding
histone binding
armadillo repeat domain binding