242685

• Gene Symbol: ATF2
• Gene Name: activating transcription factor 2
• Gene Aliases: CRE-BP1, CREB-2, CREB2, HB16, TREB7
• Chromosome Location: Chr.2: 175072250 - 175168206 on Build GRCh38
• UniGene ID: Hs.592510
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ATF2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001256090.1	NP_001243019.1	15	1715
	NM_001256091.1	NP_001243020.1	14	1640
	NM_001256092.1	NP_001243021.1	13	1583
	NM_001256093.1	NP_001243022.1	13	1615
	NM_001880.3	NP_001871.2	14	1680
	NR_045768.1		17	1877
	NR_045769.1		17	1909
	NR_045770.1		16	1762
	NR_045771.1		15	1754
	NR_045772.1		15	1692
	NR_045773.1		14	1657
	NR_045774.1		13	1565
GenBank mRNA	AK128731.1	-	14	1580
	AY029364.1	-	4	298
	BC107698.1	-	13	1550	6456836
	BC130335.1	-	13	1446	40146366
	BC130337.1	-	13	1446	40146368
	BX648469.1	-	13	1470
	DQ003036.1	-	17	1872
	DQ003037.1	-	14	1643
	DQ003038.1	-	6	560
	DQ003039.1	-	15	1717
	DQ003040.1	-	15	1655
	DQ003041.1	-	15	1678
	DQ003042.1	-	14	1581
	DQ003043.1	-	17	1840
	DQ003044.1	-	16	1725
	DQ003045.1	-	13	1546
	DQ003046.1	-	14	1620
	DQ003047.1	-	13	1528
	DQ003048.1	-	13	1578
	DQ003049.1	-	14	1603
	M31630.1	-	6	751
	X15875.1	-	12	1407

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_001025093, NM_001284374, NM_001284372, NM_001284369, NM_001284373, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
outflow tract morphogenesis
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
response to osmotic stress
cellular response to DNA damage stimulus
response to water deprivation
histone acetylation
intra-S DNA damage checkpoint
positive regulation of transforming growth factor beta2 production
positive regulation of neuron apoptotic process
fat cell differentiation
positive regulation of transcription from RNA polymerase II promoter
negative regulation of epithelial cell proliferation
regulation of sequence-specific DNA binding transcription factor activity
positive regulation of sequence-specific DNA binding transcription factor activity
adipose tissue development
amelogenesis
positive regulation of mitochondrial membrane permeability involved in apoptotic process

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
transcription factor activity, RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II activating transcription factor binding
enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
transcription coactivator activity
histone acetyltransferase activity
protein binding
cAMP response element binding protein binding
protein kinase binding
cAMP response element binding
metal ion binding
protein heterodimerization activity