242989

Gene Symbol:

RUNX1 RUNX1T1

Gene Name:

runt related transcription factor 1

RUNX1 translocation partner 1

Gene Aliases:

AML1, AML1-EVI-1, AMLCR1, CBF2alpha, CBFA2, EVI-1, PEBP2aB, PEBP2alpha

AML1-MTG8, AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2

Chromosome Location:

Chr.21: 34787801 - 35049334 on Build GRCh38

Chromosome Location:

Chr.8: 91954967 - 92103365 on Build GRCh38

UniGene ID:

Hs.149261

Hs.368431

Species:

Human

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: RUNX1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001001890.2	NP_001001890.1	2, 3	2013
	NM_001122607.1	NP_001116079.1	2, 3	2013
	NM_001754.4	NP_001745.2	5, 6	706
	XM_005261068.3	XP_005261125.1	3, 4	969
	XM_005261069.4	XP_005261126.1	5, 6	742
	XM_011529766.2	XP_011528068.1	5, 6	817
	XM_011529767.2	XP_011528069.1	4, 5	703
	XM_011529768.2	XP_011528070.1	4, 5	703
	XM_011529770.2	XP_011528072.1	5, 6	742
	XM_017028487.1	XP_016883976.1	3, 4	511
GenBank mRNA	AK226159.1	-	4, 5	703
	AK310587.1	-	5, 6	695
	BC110828.1	-	4, 5	601
	BC136380.1	-	5, 6	663	9020367
	BC136381.1	-	5, 6	662	9020368
	BC144053.1	-	5, 6	662	9052573
	D10570.1	-	2, 3	1203
	D43967.1	-	2, 3	2013
	D43968.1	-	2, 3	2013
	D43969.1	-	4, 5	960
	D89788.1	-	3, 4	403
	D89789.1	-	3, 4	403
	D89790.1	-	3, 4	403
	L34598.1	-	2, 3	1113
	S60998.1	-	2, 3	443
	S76345.1	-	1, 2	28
	S76346.1	-	1, 2	28
	U19601.1	-	4, 5	516
	X79549.1	-	2, 3	2003

Gene Symbol: RUNX1T1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	Z35296.1	-		20

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

ossification
chondrocyte differentiation
transcription from RNA polymerase II promoter
hemopoiesis
positive regulation of granulocyte differentiation
positive regulation of interleukin-2 production
positive regulation of angiogenesis
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
peripheral nervous system neuron development
hematopoietic stem cell proliferation

Function(s)

regulatory region DNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
core promoter binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
protein binding
ATP binding