243881

• Gene Symbol: NKX2-1
• Gene Name: NK2 homeobox 1
• Gene Aliases: BCH, BHC, NK-2, NKX2.1, NKX2A, NMTC1, T/EBP, TEBP, TITF1, TTF-1, TTF1
• Chromosome Location: Chr.14: 36516397 - 36520225 on Build GRCh38
• UniGene ID: Hs.94367
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NKX2-1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001079668.2	NP_001073136.1	2	425
	NM_003317.3	NP_003308.1	1	580
GenBank mRNA	BC006221.2	-	2	359	3941576
	BE796718.1	-	2	340
	BT009773.1	-	2	329
	D50740.1	-	3	483
	D50741.1	-	1	300
	U19756.1	-	1	239
	U33749.1	-	1	580
	U43203.1	-	2	411
	X82850.1	-	1	253

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_009385, NM_001146198, BC057607, BC080868, AB221567.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
neuron migration
regulation of blood volume by renin-angiotensin
transcription, DNA-templated
phospholipid metabolic process
axon guidance
brain development
endoderm development
locomotory behavior
feeding behavior
response to hormone
positive regulation of gene expression
negative regulation of epithelial to mesenchymal transition
globus pallidus development
hippocampus development
cerebral cortex cell migration
forebrain dorsal/ventral pattern formation
forebrain neuron fate commitment
cerebral cortex GABAergic interneuron differentiation
pituitary gland development
lung development
negative regulation of cell migration
negative regulation of transforming growth factor beta receptor signaling pathway
thyroid gland development
forebrain development
developmental induction
response to lipopolysaccharide
Leydig cell differentiation
hyperosmotic salinity response
positive regulation of circadian rhythm
response to ethanol
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
development of primary female sexual characteristics
rhythmic process
anatomical structure formation involved in morphogenesis
oligodendrocyte differentiation
lung saccule development
epithelial tube branching involved in lung morphogenesis
Clara cell differentiation
Type II pneumocyte differentiation

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II regulatory region DNA binding
core promoter binding
intronic transcription regulatory region sequence-specific DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
enzyme binding
transcription regulatory region DNA binding
intronic transcription regulatory region DNA binding