243

Gene Symbol:

NME2 NME1-NME2

Gene Name:

NME/NM23 nucleoside diphosphate kinase 2

NME1-NME2 readthrough

Gene Aliases:

NDKB, NDPK-B, NDPKB, NM23-H2, NM23B, PUF

NM23-LV, NMELV

Chromosome Location:

Chr.17: 51165435 - 51171744 on Build GRCh38

Chromosome Location:

Chr.17: 51153536 - 51171744 on Build GRCh38

UniGene ID:

Hs.463456

Hs.463456

Species:

Human

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: NME2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001018137.2	NP_001018147.1	4, 5	600
	NM_001018138.1	NP_001018148.1	3, 4	458
	NM_001018139.2	NP_001018149.1	4, 5	416
	NM_002512.3	NP_002503.1	4, 5	579
GenBank mRNA	BC002476.2	-	4, 5	381	3349768
	BC095458.1	-	4, 5	390	30524221
	BM556410.1	-	4, 5	416
	BT007045.1	-	3, 4	349
	CR541718.1	-	3, 4	349
	EU794639.1	-	4, 5	398
	L16785.1	-	4, 5	398
	M36981.1	-	4, 5	421
	X58965.1	-	4, 5	421

Gene Symbol: NME1-NME2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001018136.2	NP_001018146.1	7, 8	825
	NR_037149.1		8, 9	1045
GenBank mRNA	AK313448.1	-	7, 8	782
	BC107894.1	-	8, 9	947	6717551
	BC133029.1	-	7, 8	728	40147051
	BC133031.1	-	7, 8	728	40147053
	DQ109675.1	-	7, 8	745

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_138548, D13374.
This siRNA also targets the following transcripts in Mouse: NM_008704, NM_008705, NM_001077529, AK216511, M65037, and others.

Gene Ontology Categories:

Process(es)

purine nucleotide metabolic process
nucleoside diphosphate phosphorylation
GTP biosynthetic process
pyrimidine nucleotide metabolic process
UTP biosynthetic process
CTP biosynthetic process
transcription, DNA-templated
regulation of transcription, DNA-templated
cell adhesion
integrin-mediated signaling pathway
nucleoside triphosphate biosynthetic process
nucleobase-containing small molecule interconversion
peptidyl-histidine phosphorylation
negative regulation of apoptotic process
positive regulation of keratinocyte differentiation
regulation of epidermis development
positive regulation of transcription from RNA polymerase II promoter
positive regulation of epithelial cell proliferation
mitophagy in response to mitochondrial depolarization

Function(s)

DNA binding
transcription factor activity, sequence-specific DNA binding
nucleoside diphosphate kinase activity
protein histidine kinase activity
protein binding
ATP binding
metal ion binding