2453 Validated

• Gene Symbol: COMT
• Gene Name: catechol-O-methyltransferase
• Gene Aliases: HEL-S-98n
• Chromosome Location: Chr.22: 19941740 - 19969975 on Build GRCh38
• UniGene ID: Hs.370408
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: COMT
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000754.3	NP_000745.1	4, 5	740
	NM_001135161.1	NP_001128633.1	4, 5	698
	NM_001135162.1	NP_001128634.1	4, 5	715
	NM_007310.2	NP_009294.1	2, 3	471
	XM_011529886.1	XP_011528188.1	4, 5	645
	XM_017028594.1	XP_016884083.1	4, 5	964
	XM_017028595.1	XP_016884084.1	4, 5	908
GenBank mRNA	AK130031.1	-	5, 6	520
	AK290440.1	-	4, 5	678
	BC000419.2	-	4, 5	668	2964400
	BC005867.2	-	4, 5	668	2964400
	BC011935.2	-	3, 4	583	3503220
	BC100018.1	-	4, 5	730	6163659
	CR456422.1	-	3, 4	506
	CR456997.1	-	2, 3	491
	EF103918.1	-	2, 3	232
	EF103920.1	-	3, 4	221
	EF103921.1	-	3, 4	283
	EF103922.1	-	3, 4	520
	FJ224345.1	-	4, 5	668
	FJ410131.1	-	2, 3	341
	FJ410132.1	-	2, 3	491
	M58525.1	-	4, 5	695
	M65212.1	-	3, 4	569

More Information

Matching Taqman Gene Expression Assay:

Hs00241349_m1

Gene Ontology Categories:

Process(es)

female pregnancy
learning
short-term memory
estrogen metabolic process
response to organic cyclic compound
cellular response to phosphate starvation
methylation
response to lipopolysaccharide
developmental process
negative regulation of renal sodium excretion
neurotransmitter catabolic process
dopamine catabolic process
response to drug
negative regulation of dopamine metabolic process
response to pain
multicellular organismal reproductive process
negative regulation of smooth muscle cell proliferation
positive regulation of homocysteine metabolic process
regulation of sensory perception of pain

Function(s)

magnesium ion binding
protein binding
methyltransferase activity
O-methyltransferase activity
catechol O-methyltransferase activity