246788

Gene Symbol:

GH1 CSH1 CSH2 GH2

Gene Name:

growth hormone 1

chorionic somatomammotropin hormone 1

chorionic somatomammotropin hormone 2

growth hormone 2

Gene Aliases:

GH, GH-N, GHB5, GHN, IGHD1B, hGH-N

CS-1, CSA, CSMT, GHB3, PL, hCS-1, hCS-A

CS-2, CSB, GHB1, PL, hCS-B

GH-V, GHB2, GHL, GHV, hGH-V

Chromosome Location:

Chr.17: 63917193 - 63918852 on Build GRCh38

Chromosome Location:

Chr.17: 63894908 - 63896661 on Build GRCh38

Chromosome Location:

Chr.17: 63872012 - 63873729 on Build GRCh38

Chromosome Location:

Chr.17: 63880212 - 63881942 on Build GRCh38

UniGene ID:

Hs.655229

Hs.654390

Hs.654515

Hs.406754

Species:

Human

Species Specific ID (Flybase ID):

-

-

-

-

siRNA Details

Gene Symbol: GH1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000515.4	NP_000506.2	5	654
	NM_022559.3	NP_072053.1	5	609
	NM_022560.3	NP_072054.1	4	534
GenBank mRNA	A00469.1	-	5	617
	AF110644.1	-	5	450
	AF185611.1	-	6	482
	AV753220.1	-	3	474
	AY613431.1	-	5	640
	AY613432.1	-	5	640
	BC062475.1	-	5	574	30393581
	BC075012.2	-	5	605	30915404
	BC075013.2	-	5	605	30915617
	BC090045.1	-	5	621	30394115
	CD108592.1	-	4	500
	V00519.1	-	5	618

Gene Symbol: CSH1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001317.5	NP_001308.1	5	728
GenBank mRNA	AK291587.1	-	5	647
	BC002717.2	-	5	621	3631916
	BC005921.1	-	5	640	4043768
	BC020756.1	-	5	696	4769769
	BC057768.1	-	5	640	30337725
	BC062775.1	-	5	644	4604848
	BT006926.1	-	4	578
	J00118.1	-	5	607
	M25118.1	-	1	101
	V00593.1	-	4	430

Gene Symbol: CSH2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_020991.3	NP_066271.1	5	693
	NM_022644.3	NP_072170.1	4	946
	NM_022645.2	NP_072171.1	3	408
GenBank mRNA	BC022044.1	-	5	644	4769046
	BC035965.1	-	5	640	4731880
	BC119748.2	-	5	637	40119242
	V00573.1	-	5	602

Gene Symbol: GH2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002059.4	NP_002050.1	5	719
	NM_022556.3	NP_072050.1	5	674
	NM_022557.3	NP_072051.1	4	972
	NM_022558.3	NP_072052.1	5	715
GenBank mRNA	AB451332.1	-	4	533
	AB451477.1	-	4	533
	AF006060.1	-	5	545
	AF006061.1	-	4	574
	BC020760.1	-	5	640	4720475
	CR541902.1	-	4	578
	CR541924.1	-	4	578
	J03756.1	-	4	892
	M38451.1	-	5	590

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

positive regulation of receptor internalization
JAK-STAT cascade
positive regulation of activation of JAK2 kinase activity
positive regulation of phosphatidylinositol 3-kinase signaling
glucose transport
response to estradiol
positive regulation of multicellular organism growth
positive regulation of tyrosine phosphorylation of Stat3 protein
positive regulation of tyrosine phosphorylation of Stat5 protein
positive regulation of MAP kinase activity
positive regulation of insulin-like growth factor receptor signaling pathway
positive regulation of JAK-STAT cascade
positive regulation of peptidyl-tyrosine phosphorylation
growth hormone receptor signaling pathway
JAK-STAT cascade involved in growth hormone signaling pathway
bone maturation

Function(s)

growth hormone receptor binding
prolactin receptor binding
hormone activity
protein binding
growth factor activity
metal ion binding