246928

Gene Symbol:

PABPC1 PABPC3 RLIM

Gene Name:

poly(A) binding protein cytoplasmic 1

poly(A) binding protein cytoplasmic 3

ring finger protein, LIM domain interacting

Gene Aliases:

PAB1, PABP, PABP1, PABPC2, PABPL1

PABP3, PABPL3, tPABP

NY-REN-43, RNF12

Chromosome Location:

Chr.8: 100702916 - 100722998 on Build GRCh38

Chromosome Location:

Chr.13: 25096138 - 25098567 on Build GRCh38

Chromosome Location:

Chr.X: 74582976 - 74614626 on Build GRCh38

UniGene ID:

Hs.387804

Hs.458280

Hs.653288

Species:

Human

Species Specific ID (Flybase ID):

-

-

-

siRNA Details

Gene Symbol: PABPC1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002568.3	NP_002559.2	14	2352
	XM_005250861.2	XP_005250918.1	14	3263
GenBank mRNA	AK095194.1	-	14	2187
	AK130523.1	-	14	2352
	AK298990.1	-	15	2068
	AK303120.1	-	15	2076
	BC015958.2	-	15	2247	3940309
	BC023217.1	-	14	2330
	BC023520.2	-	14	2331	4123269
	BC041863.1	-	14	2976
	Y00345.1	-	14	2341
	Z48501.1	-	12	1506

Gene Symbol: PABPC3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_030979.2	NP_112241.2	1	1894
GenBank mRNA	AF132026.1	-	1	1856
	AK313336.1	-	1	1876
	AL136900.1	-	1	1876
	BC027617.2	-	1	1860	4829121
	BC045608.1	-	1	1870	5273503

Gene Symbol: RLIM
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_016120.3	NP_057204.2	4	10392
	NM_183353.2	NP_899196.1	5	10454
GenBank mRNA	AK127880.1	-	1	2241

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
nuclear-transcribed mRNA poly(A) tail shortening
mRNA splicing, via spliceosome
mRNA polyadenylation
translational initiation
gene silencing by RNA
regulation of mRNA stability
positive regulation of viral genome replication
positive regulation of translation
mRNA stabilization
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
mRNA metabolic process
negative regulation of transcription from RNA polymerase II promoter
protein polyubiquitination
transcription, DNA-templated
regulation of transcription, DNA-templated
ubiquitin-dependent protein catabolic process
protein ubiquitination
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of transcription, DNA-templated
random inactivation of X chromosome
regulation of dosage compensation by inactivation of X chromosome

Function(s)

nucleotide binding
protein binding
protein C-terminus binding
poly(A) binding
poly(U) RNA binding
translation activator activity
poly(A) RNA binding
transcription corepressor activity
ubiquitin-protein transferase activity
zinc ion binding
ligase activity
ubiquitin protein ligase activity