247208

Gene Symbol:

NCOR1 GRAPL ULK2

Gene Name:

nuclear receptor corepressor 1

GRB2 related adaptor protein like

unc-51 like autophagy activating kinase 2

Gene Aliases:

N-CoR, N-CoR1, PPP1R109, TRAC1, hN-CoR

-

ATG1B, Unc51.2

Chromosome Location:

Chr.17: 16030094 - 16216746 on Build GRCh38

Chromosome Location:

Chr.17: 19123188 - 19159187 on Build GRCh38

Chromosome Location:

Chr.17: 19770828 - 19867926 on Build GRCh38

UniGene ID:

Hs.462323

Hs.647426

Hs.168762

Species:

Human

Species Specific ID (Flybase ID):

-

-

-

siRNA Details

Gene Symbol: NCOR1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_017025396.1	XP_016880885.1	2	655
	XM_017025397.1	XP_016880886.1	2	655
	XM_017025399.1	XP_016880888.1	1	13
	XM_017025400.1	XP_016880889.1	2	655
	XM_017025401.1	XP_016880890.1	2	655
	XM_017025404.1	XP_016880893.1	2	631
	XM_017025405.1	XP_016880894.1	1	291
	XM_017025410.1	XP_016880899.1	2	636
	XM_017025416.1	XP_016880905.1	2	651

Gene Symbol: GRAPL
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_011523857.2	XP_011522159.1	5	4537

Gene Symbol: ULK2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_014683.3	NP_055498.3	27	7082
GenBank mRNA	AL080134.1	-	1	1039

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
skeletal muscle tissue development
lactation
circadian rhythm
positive regulation of cell proliferation
covalent chromatin modification
cerebellum development
cellular lipid metabolic process
negative regulation of JNK cascade
spindle assembly
regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter
regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter
negative regulation of production of miRNAs involved in gene silencing by miRNA
regulation of fatty acid transport
autophagy
signal transduction
regulation of autophagy
response to starvation
protein autophosphorylation
negative regulation of collateral sprouting
axon extension

Function(s)

RNA polymerase II regulatory region DNA binding
RNA polymerase II activating transcription factor binding
chromatin binding
transcription corepressor activity
protein binding
ligand-dependent nuclear receptor binding
protein domain specific binding
estrogen receptor binding
nuclear hormone receptor binding
histone deacetylase binding
peroxisome proliferator activated receptor binding
transcription regulatory region DNA binding
retinoid X receptor binding
thyroid hormone receptor binding
protein serine/threonine kinase activity
ATP binding