247256

Gene Symbol:

NF2 BICC1 CNN2 ELOVL7 MINOS1 PLEKHJ1 TYW1 ZNF135

Gene Name:

neurofibromin 2

BicC family RNA binding protein 1

calponin 2

ELOVL fatty acid elongase 7

mitochondrial inner membrane organizing system 1

pleckstrin homology domain containing J1

tRNA-yW synthesizing protein 1 homolog

zinc finger protein 135

Gene Aliases:

ACN, BANF, SCH

BICC, CYSRD

-

-

C1orf151, MIO10, Mic10

GNRPX

RSAFD1, TYW1A, YPL207W

ZNF61, ZNF78L1, pHZ-17, pT3

Chromosome Location:

Chr.22: 29603556 - 29698600 on Build GRCh38

Chromosome Location:

Chr.10: 58512970 - 58831437 on Build GRCh38

Chromosome Location:

Chr.19: 1026275 - 1039068 on Build GRCh38

Chromosome Location:

Chr.5: 60751789 - 60844292 on Build GRCh38

Chromosome Location:

Chr.1: 19596977 - 19629821 on Build GRCh38

Chromosome Location:

Chr.19: 2229952 - 2236724 on Build GRCh38

Chromosome Location:

Chr.7: 66996805 - 67239520 on Build GRCh38

Chromosome Location:

Chr.19: 58059227 - 58069755 on Build GRCh38

UniGene ID:

Hs.187898

Hs.100261

Hs.651512

Hs.274256

Hs.466662

Hs.501353

Hs.520917

Hs.85863

Species:

Human

Species Specific ID (Flybase ID):

-

-

-

-

-

-

-

-

siRNA Details

Gene Symbol: NF2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000268.3	NP_000259.1	16	4484
	NM_016418.5	NP_057502.2	17	4529
	NM_181828.2	NP_861966.1	16	4403
	NM_181829.2	NP_861967.1	16	4406
	NM_181830.2	NP_861968.1	15	4280
	NM_181832.2	NP_861970.1	17	4544
	NM_181833.2	NP_861971.1	5	3194
	XM_017028809.1	XP_016884298.1	16	4047
	XM_017028810.1	XP_016884299.1	17	4088
GenBank mRNA	AF369657.1	-	16	4466
	AF369658.1	-	17	4511
	AK092306.1	-	1	1375
	AK092515.1	-	1	226

Gene Symbol: BICC1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_017016677.1	XP_016872166.1	1	4106

Gene Symbol: CNN2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AK093630.1	-	1	443

Gene Symbol: ELOVL7
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001104558.1	NP_001098028.1	8	2887
	NM_001297617.1	NP_001284546.1	11	3285
	NM_001297618.1	NP_001284547.1	9	2892
	NM_024930.2	NP_079206.2	9	2938
	XM_005248606.4	XP_005248663.1	8	3502
	XM_005248607.3	XP_005248664.1	9	3215
	XM_006714695.3	XP_006714758.1	10	2994
	XM_011543651.2	XP_011541953.1	10	3184
	XM_017009885.1	XP_016865374.1	9	2875
	XM_017009886.1	XP_016865375.1	11	3114
	XM_017009887.1	XP_016865376.1	11	3305
GenBank mRNA	AB181393.1	-	9	2879
	AL137506.1	-	4	2369
	BC094792.1	-	11	3226

Gene Symbol: MINOS1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AK096240.1	-	1	523

Gene Symbol: PLEKHJ1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AK092742.1	-	2	1321

Gene Symbol: TYW1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_011516372.2	XP_011514674.1	16	3252

Gene Symbol: ZNF135
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	BM993886.1	-	1	107
	DB304820.1	-	1	89

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

mesoderm formation
negative regulation of cell-matrix adhesion
negative regulation of protein kinase activity
ectoderm development
negative regulation of DNA replication
negative regulation of cell proliferation
Schwann cell proliferation
regulation of gliogenesis
hippocampus development
negative regulation of cell-cell adhesion
actin cytoskeleton organization
negative regulation of cell growth
negative regulation of cell migration
regulation of protein stability
regulation of hippo signaling
odontogenesis of dentin-containing tooth
negative regulation of tyrosine phosphorylation of Stat3 protein
negative regulation of tyrosine phosphorylation of Stat5 protein
negative regulation of MAPK cascade
cell-cell junction organization
positive regulation of cell differentiation
negative regulation of JAK-STAT cascade
positive regulation of stress fiber assembly
lens fiber cell differentiation
regulation of stem cell proliferation
regulation of protein localization to nucleus
regulation of neural precursor cell proliferation
determination of left/right symmetry
heart development
negative regulation of canonical Wnt signaling pathway
unsaturated fatty acid biosynthetic process
fatty acid elongation, saturated fatty acid
sphingolipid biosynthetic process
fatty acid elongation, monounsaturated fatty acid
fatty acid elongation, polyunsaturated fatty acid
long-chain fatty-acyl-CoA biosynthetic process
very long-chain fatty acid biosynthetic process
tRNA processing
oxidation-reduction process

Function(s)

actin binding
integrin binding
protein binding
beta-catenin binding
protein domain specific binding
poly(A) RNA binding
fatty acid elongase activity
3-oxo-arachidoyl-CoA synthase activity
3-oxo-cerotoyl-CoA synthase activity
3-oxo-lignoceronyl-CoA synthase activity
FMN binding
lyase activity
metal ion binding
4 iron, 4 sulfur cluster binding