247459

Gene Symbol:

LINC00504 CFLAR KCNQ1OT1 SMC5-AS1 TBC1D8B UGDH-AS1

Gene Name:

long intergenic non-protein coding RNA 504

CASP8 and FADD like apoptosis regulator

KCNQ1 opposite strand/antisense transcript 1 (non-protein coding)

SMC5 antisense RNA 1 (head to head)

TBC1 domain family member 8B

UGDH antisense RNA 1

Gene Aliases:

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CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS

KCNQ1-AS2, KCNQ10T1, Kncq1, KvDMR1, KvLQT1-AS, LIT1, NCRNA00012

MAMDC2-AS2

GRAMD8B

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Chromosome Location:

Chr.4: 14470465 - 14888169 on Build GRCh38

Chromosome Location:

Chr.2: 201116015 - 201172688 on Build GRCh38

Chromosome Location:

Chr.11: 2608328 - 2699998 on Build GRCh38

Chromosome Location:

Chr.9: 70216059 - 70258874 on Build GRCh38

Chromosome Location:

Chr.X: 106802689 - 106876150 on Build GRCh38

Chromosome Location:

Chr.4: 39527839 - 39594707 on Build GRCh38

UniGene ID:

Hs.551051

Hs.390736

Hs.604823

Hs.556816

Hs.351798

Hs.640769

Species:

Human

Species Specific ID (Flybase ID):

-

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-

-

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siRNA Details

Gene Symbol: LINC00504
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_126435.1		7	1683
GenBank mRNA	BC036758.2	-	7	1695	5563071

Gene Symbol: CFLAR
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001127183.2	NP_001120655.1	10	6336
	NM_001202515.1	NP_001189444.1	6	5402
	NM_001202516.1	NP_001189445.1	8	6203
	NM_001202517.1	NP_001189446.1	9	5890
	NM_001202518.1	NP_001189447.1	8	6465
	NM_001202519.1	NP_001189448.1	9	6729
	NM_003879.5	NP_003870.4	10	6308
	XM_017005189.1	XP_016860678.1	11	7203
	XM_017005190.1	XP_016860679.1	10	6172
	XM_017005191.1	XP_016860680.1	10	6251
	XM_017005192.1	XP_016860681.1	10	7138
	XM_017005193.1	XP_016860682.1	10	9155
	XM_017005194.1	XP_016860683.1	10	7011
	XM_017005195.1	XP_016860684.1	11	6349
	XM_017005196.1	XP_016860685.1	8	5974

Gene Symbol: KCNQ1OT1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_002728.3		1	63549

Gene Symbol: SMC5-AS1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	CR936772.1	-	3	5345

Gene Symbol: TBC1D8B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	BX648230.1	-	7	2704

Gene Symbol: UGDH-AS1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_047679.1		5	1561
GenBank mRNA	AK056558.1	-	5	1381

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

proteolysis
apoptotic process
skeletal muscle tissue development
skeletal muscle atrophy
regulation of skeletal muscle satellite cell proliferation
skeletal myofibril assembly
viral process
negative regulation of apoptotic process
positive regulation of catalytic activity
positive regulation of I-kappaB kinase/NF-kappaB signaling
skeletal muscle tissue regeneration
positive regulation of NF-kappaB transcription factor activity
regulation of necroptotic process
execution phase of apoptosis
negative regulation of myoblast fusion
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

protease binding
death receptor binding
protein binding
enzyme activator activity
protein complex binding
cysteine-type endopeptidase activity involved in execution phase of apoptosis