247812

Gene Symbol:

LOC100506290 CFLAR ERVK-1 FKSG48 FKSG49 HELLPAR LOC402469 METTL21A NEK5 SEC11A SPICE1

Gene Name:

uncharacterized LOC100506290

CASP8 and FADD like apoptosis regulator

endogenous retrovirus group K member 1

FKSG48

FKSG49

HELLP associated long non-coding RNA

uncharacterized LOC402469

methyltransferase like 21A

NIMA related kinase 5

SEC11 homolog A, signal peptidase complex subunit

spindle and centriole associated protein 1

Gene Aliases:

-

CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS

c1_A

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FKSG52, FKSG55, FKSG56, FKSG57, FKSG60, FKSG61, FKSG64, FKSG65, FKSG66, FKSG67, FKSG68, FKSG70

LINC-HELLP, lncHELLP

FKSG50, FKSG53, FKSG54

FAM119A, HCA557b, HSPA-KMT

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1810012E07Rik, SEC11L1, SPC18, SPCS4A, sid2895

CCDC52, SPICE

Chromosome Location:

-

Chromosome Location:

Chr.2: 201116015 - 201172688 on Build GRCh38

Chromosome Location:

-

Chromosome Location:

-

Chromosome Location:

-

Chromosome Location:

-

Chromosome Location:

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Chromosome Location:

Chr.2: 207580631 - 207625928 on Build GRCh38

Chromosome Location:

Chr.13: 52064762 - 52129092 on Build GRCh38

Chromosome Location:

Chr.15: 84669537 - 84716460 on Build GRCh38

Chromosome Location:

Chr.3: 113442718 - 113515187 on Build GRCh38

UniGene ID:

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Hs.390736

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-

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Hs.160562

-

Hs.664764

Hs.672144

Hs.9534

Hs.477144

Species:

Human

Species Specific ID (Flybase ID):

-

-

-

-

-

-

-

-

-

-

-

siRNA Details

Gene Symbol: LOC100506290
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AF336880.1	-	1	282

Gene Symbol: CFLAR
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001127183.2	NP_001120655.1	10	3901
	NM_001202515.1	NP_001189444.1	6	2967
	NM_001202516.1	NP_001189445.1	8	3768
	NM_001202517.1	NP_001189446.1	9	3455
	NM_001202518.1	NP_001189447.1	8	4030
	NM_001202519.1	NP_001189448.1	9	4294
	NM_003879.5	NP_003870.4	10	3873
	XM_017005189.1	XP_016860678.1	11	4768
	XM_017005190.1	XP_016860679.1	10	3737
	XM_017005191.1	XP_016860680.1	10	3816
	XM_017005192.1	XP_016860681.1	10	4703
	XM_017005193.1	XP_016860682.1	10	6720
	XM_017005194.1	XP_016860683.1	10	4576
	XM_017005195.1	XP_016860684.1	11	3914
	XM_017005196.1	XP_016860685.1	8	3539

Gene Symbol: ERVK-1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	BQ304053.1	-	1	65

Gene Symbol: FKSG48
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AF336875.1	-	1	276

Gene Symbol: FKSG49
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AF336878.1	-	1	201
	AF336879.1	-	1	225
	AF336882.1	-	1	261
	AF336883.1	-	1	210
	AF336884.1	-	1	270
	AF336886.1	-	1	198
	AF338190.1	-	1	243
	AF338193.1	-	1	261
	AF338194.1	-	1	264
	AF338195.1	-	1	261
	AF338196.1	-	1	273
	AF338198.1	-	1	261
	AF469044.1	-	1	210

Gene Symbol: HELLPAR
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	JX088243.1	-	1	53409

Gene Symbol: LOC402469
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AF336877.1	-	1	273
	AF336881.1	-	1	273
	AF338191.1	-	1	258

Gene Symbol: METTL21A
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001127395.2	NP_001120867.1	4	2323
	NM_145280.5	NP_660323.3	4	2184

Gene Symbol: NEK5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_199289.2	NP_954983.1	22	2907
GenBank mRNA	BC063885.1	-	22	2893	30383658

Gene Symbol: SEC11A
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AB209437.1	-	1	414

Gene Symbol: SPICE1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AL832327.2	-	12	3048

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

proteolysis
apoptotic process
skeletal muscle tissue development
skeletal muscle atrophy
regulation of skeletal muscle satellite cell proliferation
skeletal myofibril assembly
viral process
negative regulation of apoptotic process
positive regulation of catalytic activity
positive regulation of I-kappaB kinase/NF-kappaB signaling
skeletal muscle tissue regeneration
positive regulation of NF-kappaB transcription factor activity
regulation of necroptotic process
execution phase of apoptosis
negative regulation of myoblast fusion
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway
protein methylation
peptidyl-lysine methylation
regulation of ATPase activity
protein phosphorylation
positive regulation of striated muscle cell differentiation
positive regulation of cysteine-type endopeptidase activity

Function(s)

protease binding
death receptor binding
protein binding
enzyme activator activity
protein complex binding
cysteine-type endopeptidase activity involved in execution phase of apoptosis
protein-lysine N-methyltransferase activity
Hsp70 protein binding
ATPase binding
protein serine/threonine kinase activity
ATP binding
metal ion binding