247870

Gene Symbol:

CLEC2D BLNK FANCB NPM1

Gene Name:

C-type lectin domain family 2 member D

B-cell linker

Fanconi anemia complementation group B

nucleophosmin

Gene Aliases:

CLAX, LLT1, OCIL

AGM4, BASH, BLNK-S, LY57, SLP-65, SLP65, bca

FA2, FAAP90, FAAP95, FAB, FACB

B23, NPM

Chromosome Location:

Chr.12: 9669708 - 9699555 on Build GRCh38

Chromosome Location:

Chr.10: 96189171 - 96271576 on Build GRCh38

Chromosome Location:

Chr.X: 14690863 - 14873255 on Build GRCh38

Chromosome Location:

Chr.5: 171387648 - 171410900 on Build GRCh38

UniGene ID:

Hs.268326

Hs.665244

Hs.554740

Hs.557550

Species:

Human

Species Specific ID (Flybase ID):

-

-

-

-

siRNA Details

Gene Symbol: CLEC2D
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001004419.4	NP_001004419.1	6	1292
	NM_001197317.2	NP_001184246.1	4	1099
	NM_001197318.2	NP_001184247.1	4	1106
	NM_001197319.2	NP_001184248.1	3	995
	NM_013269.5	NP_037401.1	5	1210
	NR_036693.2		4	1181
GenBank mRNA	AK310554.1	-	4	1172
	BC094859.1	-	1	87

Gene Symbol: BLNK
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_011539728.2	XP_011538030.1	17	3276
	XM_017016159.1	XP_016871648.1	16	3208

Gene Symbol: FANCB
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_017029356.1	XP_016884845.1	11	3475

Gene Symbol: NPM1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001037738.2	NP_001032827.1	2	343
	NM_002520.6	NP_002511.1	2	343
	NM_199185.3	NP_954654.1	2	343
	XM_005265920.3	XP_005265977.1	2	399
GenBank mRNA	AB042278.1	-	2	98
	AB451236.1	-	2	98
	AB451361.1	-	2	98
	AK290652.1	-	2	206
	AY347529.1	-	3	233
	AY740634.1	-	2	170
	AY740635.1	-	2	170
	AY740636.1	-	2	170
	AY740637.1	-	2	170
	AY740638.1	-	2	170
	AY740639.1	-	2	170
	AY740640.1	-	2	170
	BC002398.2	-	2	185	2821577
	BC008495.1	-	2	195	4276604
	BC009623.2	-	2	224	3877633
	BC012566.1	-	2	198	4097025
	BC014349.1	-	2	194	3511037
	BC016716.1	-	2	197	4068167
	BC016768.1	-	2	197	4081364
	BC016824.1	-	2	197	4106286
	BC020467.1	-	2	184
	BC021668.1	-	2	198	3930893
	BC021983.1	-	2	196	4106023
	BC050628.1	-	2	184	5575414
	BC107754.1	-	2	199	6736004
	BP291033.1	-	2	253
	BT007011.1	-	2	98
	DQ303464.1	-	2	194
	EF429251.1	-	2	98
	KU178236.1	-	2	98
	KU178237.1	-	2	98
	M23613.1	-	2	191
	M26697.1	-	2	188
	M28699.1	-	2	185
	X16934.1	-	2	58

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

cell surface receptor signaling pathway
regulation of immune response
inflammatory response
humoral immune response
transmembrane receptor protein tyrosine kinase signaling pathway
positive regulation of signal transduction
B cell differentiation
intracellular signal transduction
interstrand cross-link repair
DNA repair
nucleosome assembly
intracellular protein transport
nucleocytoplasmic transport
response to stress
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
centrosome cycle
signal transduction
cell aging
protein localization
positive regulation of cell proliferation
negative regulation of cell proliferation
negative regulation of centrosome duplication
viral process
regulation of endodeoxyribonuclease activity
CENP-A containing nucleosome assembly
ribosome assembly
negative regulation of apoptotic process
negative regulation of protein kinase activity by regulation of protein phosphorylation
positive regulation of translation
positive regulation of transcription, DNA-templated
regulation of centriole replication
positive regulation of NF-kappaB transcription factor activity
protein oligomerization
regulation of endoribonuclease activity
regulation of eIF2 alpha phosphorylation by dsRNA
positive regulation of cell cycle G2/M phase transition

Function(s)

transmembrane signaling receptor activity
carbohydrate binding
transmembrane receptor protein tyrosine kinase adaptor activity
SH3/SH2 adaptor activity
protein binding
transcription coactivator activity
RNA binding
protein kinase inhibitor activity
protein kinase binding
Tat protein binding
histone binding
protein homodimerization activity
ribosomal large subunit binding
ribosomal small subunit binding
poly(A) RNA binding
protein heterodimerization activity
NF-kappaB binding
unfolded protein binding