247872

Gene Symbol:

NPM1 BLNK FANCB

Gene Name:

nucleophosmin

B-cell linker

Fanconi anemia complementation group B

Gene Aliases:

B23, NPM

AGM4, BASH, BLNK-S, LY57, SLP-65, SLP65, bca

FA2, FAAP90, FAAP95, FAB, FACB

Chromosome Location:

Chr.5: 171387648 - 171410900 on Build GRCh38

Chromosome Location:

Chr.10: 96189171 - 96271576 on Build GRCh38

Chromosome Location:

Chr.X: 14690863 - 14873255 on Build GRCh38

UniGene ID:

Hs.557550

Hs.665244

Hs.554740

Species:

Human

Species Specific ID (Flybase ID):

-

-

-

siRNA Details

Gene Symbol: NPM1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001037738.2	NP_001032827.1	4, 5	602
	NM_002520.6	NP_002511.1	4, 5	602
	NM_199185.3	NP_954654.1	4, 5	602
	XM_005265920.3	XP_005265977.1	4, 5	658
	XM_011534564.1	XP_011532866.1	3, 4	422
GenBank mRNA	AB042278.1	-	4, 5	357
	AB451236.1	-	4, 5	357
	AB451361.1	-	4, 5	357
	AK000472.1	-	2, 3	165
	AK290652.1	-	4, 5	465
	AY347529.1	-	5, 6	492
	AY740634.1	-	4, 5	429
	AY740635.1	-	4, 5	429
	AY740636.1	-	4, 5	429
	AY740637.1	-	4, 5	429
	AY740638.1	-	4, 5	429
	AY740639.1	-	4, 5	429
	AY740640.1	-	4, 5	429
	BC002398.2	-	4, 5	444	2821577
	BC003670.1	-	1	159
	BC008495.1	-	4, 5	454	4276604
	BC009623.2	-	4, 5	483	3877633
	BC012566.1	-	4, 5	457	4097025
	BC014349.1	-	4, 5	453	3511037
	BC016716.1	-	4, 5	456	4068167
	BC016768.1	-	4, 5	456	4081364
	BC016824.1	-	4, 5	456	4106286
	BC020467.1	-	4, 5	443
	BC021668.1	-	4, 5	457	3930893
	BC021983.1	-	4, 5	455	4106023
	BC050628.1	-	4, 5	443	5575414
	BC107754.1	-	4, 5	458	6736004
	BT007011.1	-	4, 5	357
	DQ303464.1	-	4, 5	453
	EF429251.1	-	4, 5	357
	KU178236.1	-	4, 5	357
	KU178237.1	-	4, 5	357
	M23613.1	-	4, 5	450
	M26697.1	-	4, 5	447
	M28699.1	-	4, 5	444
	X16934.1	-	4, 5	317

Gene Symbol: BLNK
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_011539728.2	XP_011538030.1	17	3534
	XM_017016159.1	XP_016871648.1	16	3466

Gene Symbol: FANCB
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_017029356.1	XP_016884845.1	11	3734

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

DNA repair
nucleosome assembly
intracellular protein transport
nucleocytoplasmic transport
response to stress
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
centrosome cycle
signal transduction
cell aging
protein localization
positive regulation of cell proliferation
negative regulation of cell proliferation
negative regulation of centrosome duplication
viral process
regulation of endodeoxyribonuclease activity
CENP-A containing nucleosome assembly
ribosome assembly
negative regulation of apoptotic process
negative regulation of protein kinase activity by regulation of protein phosphorylation
positive regulation of translation
positive regulation of transcription, DNA-templated
regulation of centriole replication
positive regulation of NF-kappaB transcription factor activity
protein oligomerization
regulation of endoribonuclease activity
regulation of eIF2 alpha phosphorylation by dsRNA
positive regulation of cell cycle G2/M phase transition
inflammatory response
humoral immune response
transmembrane receptor protein tyrosine kinase signaling pathway
positive regulation of signal transduction
B cell differentiation
intracellular signal transduction
interstrand cross-link repair

Function(s)

transcription coactivator activity
RNA binding
protein kinase inhibitor activity
protein binding
protein kinase binding
Tat protein binding
histone binding
protein homodimerization activity
ribosomal large subunit binding
ribosomal small subunit binding
poly(A) RNA binding
protein heterodimerization activity
NF-kappaB binding
unfolded protein binding
transmembrane receptor protein tyrosine kinase adaptor activity
SH3/SH2 adaptor activity